经鼻内窥镜垂体瘤切除术对垂体瘤患者应激因子水平的影响

doi:10.3969/j.issn.1671-7171.2021.03.026

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Abstract 【Objective】To investigate the effect of endoscopic pituitary tumor resection on stress factors in patients with pituitary tumor.【Methods】 The clinical data of 62 patients with pituitary adenomas admitted to our hospital from August 2016 to June 2019 were retrospectively analyzed. According to different surgical methods, they were divided into observation group (single nostril transsphenoidal approach pituitary adenoma resection under nasal endoscope) and control group (transsphenoidal approach pituitary adenoma resection under microscope), 31 cases in each group. The curative effect, postoperative stress factors and complication rate of the two groups were analyzed. 【Results】The operation time and postoperative hospital stay of the observation group were shorter than those of the control group, the intraoperative blood loss and the proportion of total tumor resection of the observation group were lower than those of the control group, the difference was statistically significant ( P <0.05). Three days after operation, the levels of serum high sensitivity C-reactive protein (hs CRP), interleukin-8 (IL-8), growth hormone (GH), prolactin (PRL) and adrenocorticotropic hormone (ACTH) in the two groups were higher than those before operation, and those in the observation group were lower than those in the control group ( P <0.05). The incidence of postoperative complications in the observation group was significantly lower than that in the control group ( χ² =0.029, P =0.05).【Conclusion】Transnasal endoscopic pituitary adenoma resection has the advantages of less trauma, less blood loss and less stress response to the body, which is conducive to improving endocrine factors and has high safety.

Key words： Pituitary Neoplasms/SU Nasal Cavity Endoscopy Hormones/BL C-Reactive Protein/BL

Received: 22 May 2019

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R736.4

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	QIAO Zhi-qiang

Cite this article:

QIAO Zhi-qiang. Effect of Transnasal Endoscopic Pituitary Tumor Resection on Stress Factors in Patients with Pituitary Tumor[J]. JOURNAL OF CLINICAL RESEARCH, 2021, 38(3): 410-412.

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http://journal07.magtech.org.cn/yxlcyj/EN/10.3969/j.issn.1671-7171.2021.03.026 OR http://journal07.magtech.org.cn/yxlcyj/EN/Y2021/V38/I3/410

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