医学临床研究
   Apr. 4, 2025    Home  |  About Journal  |  Editorial Board  |  Instruction  |  Subscribe  |  Advertisement  |  Messages Board  |  Contact Us  |  中文
JOURNAL OF CLINICAL RESEARCH  2020, Vol. 37 Issue (12): 1844-1846    DOI: 10.3969/j.issn.1671-7171.2020.12.025
Current Issue | Archive | Adv Search |
Correlation between Prognosis and Depth of Invasion and Postoperative Chemotherapy in Primary Bladder Adenocarcinoma
ZHANG Lu, DUAN Wei, SUN Xiao-dong, et al
Department of Oncology, Yan'an University Affiliated Hospital, Yan'an, Shaanxi 716000
Download: PDF (0 KB)   HTML (1 KB) 
Export: BibTeX | EndNote (RIS)      
Abstract  【Objective】To investigate the effect of tumor invasion depth and postoperative adjuvant chemotherapy on the prognosis of patients with primary bladder adenocarcinoma. 【Methods】 A total of 78 patients with primary bladder adenocarcinoma treated in our hospital were divided into survival group (49 cases) and death group (29 cases) according to the 3-year follow-up results. The age, gender, operation mode, pathological stage, pathological differentiation degree, tumor number, maximum diameter of lesion, depth of invasion, lymph node metastasis and postoperative adjuvant chemotherapy were compared between the two groups. Cox proportional hazard regression model was used to analyze the related factors affecting the prognosis of patients. 【Results】There was no significant difference in age, gender, operation mode, tumor number and maximum diameter between the two groups (P>0.05); there were significant differences in pathological stage, tumor differentiation degree, depth of invasion, postoperative adjuvant chemotherapy between survival group and death group (P<0.05); Cox proportional hazard model analysis showed that: the increased pathological stage of primary bladder adenocarcinoma, the decreased tumor differentiation and myometrial invasion were independent risk factors for poor prognosis (P<0.05). Postoperative adjuvant chemotherapy had no significant effect on the prognosis of patients (P>0.05). 【Conclusion】There are many factors that affect the prognosis of patients with primary bladder adenocarcinoma. Myometrial invasion is one of the independent risk factors. However, the effect of postoperative adjuvant chemotherapy on prognosis is not significant, which may need to be further extended for further study.
Key wordsUrinary Bladder Neoplasms      Adenocarcinoma      Prognosis     
Received: 08 May 2020     
PACS:  R737.14  
Service
E-mail this article
Add to my bookshelf
Add to citation manager
E-mail Alert
RSS
Articles by authors
Cite this article:   
URL:  
http://journal07.magtech.org.cn/yxlcyj/EN/10.3969/j.issn.1671-7171.2020.12.025     OR     http://journal07.magtech.org.cn/yxlcyj/EN/Y2020/V37/I12/1844
Copyright © Editorial Board of JOURNAL OF CLINICAL RESEARCH
Supported by:Beijing Magtech