Abstract：【Objective】To investigate the effect of non-exfoliating dot matrix laser combined with finasteride and minoxidil tincture in the treatment of androgenic alopecia.【Methods】A total of 80 male patients with androgenic alopecia admitted to our hospital from January 2022 to December 2023 were selected and divided into the control group (treated with finasteride and minoxidil tincture) and the observation group (treated with non-stripping dot matrix laser combined with finasteride and minoxidil tincture) according to random number table method, with 40 cases in each group. The clinical efficacy, hair growth (hair density, hair thickness, proportion of empty hair follicles), trichoscopic signs (hair diameter thinning > 20%, cellular pigmentation, local absence of hair, white scale, brown peri-hair sign, yellow dot sign, white dot sign) and adverse reactions were compared between the two groups.【Results】The total effective rate of the observation group was higher than that of the control group (P<0.05). After treatment, the hair density of the two groups was higher than before treatment, and the proportion of empty hair follicles was lower than before treatment (P<0.05). The hair density of the observation group was higher than that of the control group, and the proportion of empty hair follicles was lower than that of the control group (P<0.05). There was no statistical significance in hair coarseness between the two groups before and after treatment (P>0.05). After treatment, the proportion of hair diameter finer, local no hair sign and yellow dot in observation group was lower than that in control group (P<0.05). There was no statistical significance in the situation of honeycomb pigmentation, white scale, brown peri-hair sign and white dot sign between the two groups (P>0.05). There was no significant difference in the total incidence of adverse reactions between the two groups (P>0.05).【Conclusion】Non-stripping dot matrix laser combined with finasteride and minoxidil tincture in the treatment of male patients with androgenic alopecia has a good effect, can improve the physiological condition of hair follicles, promote hair growth, and has a good safety, worthy of clinical application.
杨晓娟. 非剥脱点阵激光联合非那雄胺、米诺地尔酊治疗雄性激素源性脱发男性患者的临床疗效[J]. 医学临床研究, 2025, 42(2): 282-284.
YANG Xiaojuan. Clinical Effect of Non-stripping Dot Matrix Laser Combined with Finasteride and Minoxidil Tincture on Male Patients with Androgenic Alopecia. JOURNAL OF CLINICAL RESEARCH, 2025, 42(2): 282-284.
2025, Vol. 42 
