Abstract：【Objective】To investigate the ultrasonic characteristics of Hashimoto's thyroiditis (HT) combined with TI-RADS in the 4 types of benign and malignant nodules.【Methods】From January to May 2024, 136 patients clinically diagnosed as HT with TI-RADS type 4 nodules in our hospital were examined by ultraso-guided fine needle aspiration cytology(US-FNAC) to analyze the ultrasonic characteristics of nodules and compare them with Bethesda classification results. According to the results of Bethesda classification, they were divided into the benign group (Bethesda grade Ⅱ) and the malignant group (grade Ⅴ+Ⅵ). The correlation between the ultrasonic features of nodules and the benign and malignant nodules was analyzed, and the independent risk factors for malignant nodules of type 4 of HT combined with TI-RADS were predicted.【Results】Univariate analysis showed that the type of nodule echo, edge and strong echo were correlated with the malignancy of nodule (P<0.05), but the solid structure of nodule, whether there was strong focal echo, shape and location were not correlated with the malignancy of nodule (P>0.05). The results of multi-factor analysis showed that low echo and strong focal echo type HT combined with TI-RADS type 4 nodules were independent risk factors for malignancy. The proportion of coarse calcification in the malignant group was lower than that in the benign group, and the proportion of microcalcification was higher than that in the benign group, with statistical significance (P<0.05).【Conclusion】Among the 4 types of TI-RADS nodules with HT, the malignant risk of low echo and dot strong echo nodules is higher.
2025, Vol. 42 
