医学临床研究
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医学临床研究  2024, Vol. 41 Issue (1): 66-69    DOI: 10.3969/j.issn.1671-7171.2024.01.018
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白细胞/平均血小板体积预测STEMI患者远期预后的临床价值
齐建钢1, 柳锡琴2*
1.铜川市中医医院疾控科,陕西 铜川 727031;
2.陕西省平利县中医医院检验科,陕西 安康 725500
Clinical Value of Predicting Long-term Prognosis of STEMI Patients with White Blood Cell/Average Platelet Volume
QI Jiangang, LIU Xiqin
Tongchuan Traditional Chinese Medicine Hospital,Tongchuan Shaanxi 727031
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摘要 【目的】 探讨白细胞/平均血小板体积(WMR)预测急性ST段抬高型心肌梗死(STEMI)患者远期预后的临床价值。【方法】 选择2017年5月至2019年9月铜川市中医医院心内科收治的161例行经皮冠状动脉介入术(PCI)治疗的急性STEMI患者,根据患者临床预后将患者分为预后良好组(n=32)及预后不良组(n=129)。比较两组患者临床指标,采用多因素Logistic回归分析临床指标与急性STEMI患者远期预后不良的相关性,采用受试者工作特征(ROC)曲线评估相关临床指标预测急性STEMI患者远期预后的价值。【结果】 预后良好组患者心肌肌钙蛋白I(cTnI)、低密度脂蛋白胆固醇(LDL-C)、血常规[白细胞(WBC)计数、血小板平均体积(MPV)]水平显著低于预后不良组,左心室射血分数(LVEF)高于预后不良组,差异有统计学意义(P<0.05)。多元Logistic回归分析显示,WMR、cTnI、MPV、LVEF与急性STEMI患者预后不良相关(P<0.05),其优势比(OR)分别为3.41、5.18、1.18、0.91。ROC曲线分析显示,cTnI预测STEMI患者预后不良的价值最高,显著高于WMR、MPV及LVEF(P<0.01);WMR预测STEMI患者预后不良的价值高于MPV及LVEF(P<0.05);WMR最佳诊断界值为0.63。Kaplan-Meier生存曲线分析显示,高WMR组无主要不良心血管事件生存时间显著少于低WMR组(P=0.033)。【结论】 WMR是潜在预测STEMI患者远期预后的临床指标,值得临床借鉴参考。
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齐建钢
柳锡琴
关键词 心肌梗死急性病白细胞平均血小板体积预后    
Abstract:【Objective】 To investigate the clinical value of white blood cell/mean platelet volume (WMR) in predicting the long-term prognosis of patients with acute ST-segment elevation myocardial infarction (STEMI). 【Methods】 A total of 161 patients with acute STEMI admitted to the Cardiology Department of our hospital from May 2017 to September 2019 were selected and treated with percutaneous coronary intervention (PCI). The patients were divided into a good prognosis group (n=32) and a poor prognosis group (n=129) based on their clinical prognosis. The clinical indicators of the two groups were compared, and multivariate logistic regression analysis was used to analyze the correlation between clinical indicators and long-term adverse prognosis of acute STEMI patients. The receiver operating characteristic (ROC) curve was used to evaluate the value of relevant clinical indicators in predicting the long-term prognosis of acute STEMI patients. 【Results】 The levels of cTnI, LDL-C, WBC, MPV, and WMR in the good prognosis group were significantly lower than those in the poor prognosis group, but the LVEF was higher than that in the poor prognosis group, with statistically significant differences (P<0.05). Multivariate logistic regression analysis showed that WMR, cTnI, MPV, and LVEF were associated with adverse prognosis in patients with acute STEMI (P<0.05), with odds ratios of 3.41, 5.18, 1.18, and 0.91, respectively. ROC curve analysis showed that cTnI had the highest predictive value for adverse prognosis in STEMI patients, significantly higher than WMR, MPV, and LVEF (P<0.01); WMR had a higher predictive value for adverse prognosis in STEMI patients than MPV and LVEF (P<0.05); the optimal diagnostic threshold of WMR was 0.63. Kaplan-Meier survival curve analysis showed that the survival time without major adverse cardiovascular events (MACEs) in the high WMR group was significantly lower than that in the low WMR group (P=0.033). 【Conclusion】 WMR is a potential clinical indicator for predicting the long-term prognosis of STEMI patients and is worthy of clinical reference.
Key wordsMyocardial Infarction    Acute Disease    White Blood Cell    Mean Platelet Volume    Prognosis
收稿日期: 2022-04-27     
中图分类号:  R542.22  
通讯作者: *E-mail:LXQ18992508256@163.com   
引用本文:   
齐建钢, 柳锡琴. 白细胞/平均血小板体积预测STEMI患者远期预后的临床价值[J]. 医学临床研究, 2024, 41(1): 66-69.
QI Jiangang, LIU Xiqin. Clinical Value of Predicting Long-term Prognosis of STEMI Patients with White Blood Cell/Average Platelet Volume. JOURNAL OF CLINICAL RESEARCH, 2024, 41(1): 66-69.
链接本文:  
http://journal07.magtech.org.cn/yxlcyj/CN/10.3969/j.issn.1671-7171.2024.01.018     或     http://journal07.magtech.org.cn/yxlcyj/CN/Y2024/V41/I1/66
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