Abstract：【Objective】To investigate the effect of tetracaine mucilage combined with etomidate in the removal of double-J tube. 【Methods】A total of 180 patients undergoing cystoscopy-assisted double-J tube removal were randomly divided into tetracaine mucilage group(group A),tetracaine mucilage combined with etomidate group(group B),and fentanyl combined with etomidate group(group C),with 60 cases in each group.The mean arterial pressure(MAP),heart rate(HR),pulse oximetry(SpO2),respiratory rate(RR),and adverse reactions during the operation were compared at each time point of the patients' lithotomy position(T0),2 minutes after administration(T1),after entering the bladder(T2),and after removing the double-J tube(T3). The operation time and postoperative urethral pain stimulation [visual analog scale(VAS)] scores were also compared. The satisfaction of patients,operating physicians,and anesthesiologists was compared. 【Results】The MAP,RR,and HR at T2 and T3 in group A were higher than those in group B and C(P<0.05);the MAP,RR,and SpO2 at T1 in group C were lower than those in group A and B(P<0.05);the incidence of body movement during the operation in group A was higher than that in group B and C,while the incidence of myoclonus was lower than that in group B and C(both P<0.05);the incidence of respiratory depression,dizziness,nausea,and vomiting in group C was higher than that in group A and B(P<0.05);the operation time and VAS scores at 10 minutes and 1 hour after surgery in group A were higher than those in group B and C(P<0.05);the VAS score at 2 hours after surgery in group B was lower than that in group A and C(P<0.05);the satisfaction of patients,operating physicians,and anesthesiologists in group B was higher than that in group A and C(P<0.05). 【Conclosion】The effect of tetracaine mucilage combined with etomidate in the removal of double-J tube is better,with the advantages of short-term analgesia,sedation,and less adverse reactions.
张龙, 蒋晖, 杨仪莹, 邓利兵, 杨传信, 周海洲, 沙勤, 梁婧. 丁卡因胶浆复合依托咪酯在拔除双J管术中的应用效果*[J]. 医学临床研究, 2023, 40(11): 1620-1623.
ZHANG Long, JIANG Hui, YANG Yiying, et al. Study on the Effect of Tetracaine Mucilage Combined with Etomidate in the Removal of Double-J Tube. JOURNAL OF CLINICAL RESEARCH, 2023, 40(11): 1620-1623.
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