新诊断2型糖尿病患者骨质疏松的影响因素分析

doi:10.3969/j.issn.1671-7171.2023.06.007

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摘要【目的】探讨新诊断2型糖尿病患者骨质疏松的影响因素。【方法】选取2020年3月至2022年3月在本院就诊的新诊断2型糖尿病患者300例,采用双能X射线骨密度仪测量腰椎(L_1～4)骨密度(BMD),根据患者BMD值分为骨量正常组(n=59)、骨量减少组(n=158)、骨质疏松组(n=83),分析新诊断2型糖尿病患者骨质疏松的影响因素。【结果】 300例新诊断的2型糖尿病患者中,骨量减少158例,占52.67%,骨质疏松83例,占27.67%。骨质疏松组年龄均大于骨量减少组及骨量正常组,而高密度脂蛋白胆固醇(HDL-C)均低于骨量减少组及骨量正常组。Logistic回归分析结果显示:年龄与新诊断2型糖尿病发生骨量减少及骨质疏松呈显著正相关(P<0.05),HDL-C与新诊断2型糖尿病发生骨量减少及骨质疏松呈显著负相关(P<0.05)。【结论】新诊断2型糖尿病患者骨量减少及骨质疏松的发病率明显升高,年龄、HDL-C是新诊断2型糖尿病患者骨质疏松的影响因素。

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关键词 ：糖尿病,2型, 骨质疏松, 影响因素分析

Abstract：【Objective】 To explore the influencing factors of osteoporosis in newly diagnosed type 2 diabetes patients. 【Methods】 A total of 300 newly diagnosed patients with type 2 diabetes from March 2020 to March 2022 were selected. Bone mineral density (BMD) of lumbar spine (L_1-4) was measured by dual energy X-ray absorptiometry. According to the BMD value of patients,they were divided into normal bone mass group (n=59),osteopenia group (n=158),and osteoporosis group (n=83). The influencing factors of osteoporosis in newly diagnosed type 2 diabetes patients were analyzed. 【Results】 Among 300 newly diagnosed type 2 diabetes patients,158 cases had bone mass reduction (52.67%),and 83 cases had osteoporosis (27.67%). The age of osteoporosis group was higher than that of osteopenia group and normal bone mass group,while high-density lipoprotein cholesterol (HDL-C) was lower than that of osteopenia group and normal bone mass group. Logistic regression analysis showed that age was significantly positively correlated with the occurrence of osteopenia and osteoporosis in newly diagnosed type 2 diabetes (P<0.05),and HDL-C was significantly negatively correlated with the occurrence of osteopenia and osteoporosis in newly diagnosed type 2 diabetes (P<0.05). 【Conclusion】 The incidence rate of osteoporosis and osteopenia in newly diagnosed type 2 diabetes patients is significantly increased. Age and HDL-C are the influencing factors of osteoporosis in newly diagnosed type 2 diabetes patients.

Key words： Diabetes Mellitus,Type 2 Osteoporosis Root Cause Analysis

收稿日期: 2023-03-14

中图分类号:

R587.1

基金资助:湖南省卫生健康委科研计划项目资助(编号:20201280)

通讯作者: **E-mail:375854167@qq.com

引用本文:

钟如意, 邱新文, 陈胜, 胡芳琳, 李芬. 新诊断2型糖尿病患者骨质疏松的影响因素分析[J]. 医学临床研究, 2023, 40(6): 824-826.
ZHONG Ru-yi, QIU Xin-wen, CHEN Sheng, et al. Analysis of Influencing Factors of Osteoporosis in Newly Diagnosed Type 2 Diabetes Patients. JOURNAL OF CLINICAL RESEARCH, 2023, 40(6): 824-826.

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http://journal07.magtech.org.cn/yxlcyj/CN/10.3969/j.issn.1671-7171.2023.06.007 或 http://journal07.magtech.org.cn/yxlcyj/CN/Y2023/V40/I6/824

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