实时剪切波弹性成像评估健康儿童甲状腺杨氏模量值的参考范围及其影响因素

doi:10.3969/j.issn.1671-7171.2022.09.012

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摘要【目的】探讨实时剪切波弹性成像(SWE)技术评估健康儿童甲状腺杨氏模量最大值(E_max)、最小值(E_min)、平均值(E_mean)的参考范围及其影响因素。【方法】选取在湖南省儿童医院行SWE检查并记录相关E_max、E_min、E_mean的314例健康儿童,比较健康儿童不同性别、不同年龄、左右长轴的甲状腺杨氏弹性模量值E_max、E_min、E_mean的差异。【结果】 314例健康儿童甲状腺杨氏模量E_max、E_min、E_mean分别为(13.630±3.520)KPa、(9.160±2.927)KPa、(11.189±3.127)KPa。健康儿童不同性别、左右长轴甲状腺杨氏模量值E_max、E_min、E_mean比较,差异无统计学意义(P>0.05);不同年龄健康儿童甲状腺杨氏模量值E_max、E_min、E_mean比较,差异有统计学意义(P<0.05)。【结论】 SWE作为一种定量、无创性检测甲状腺硬度的检查方法,依据所收集的数据能计算健康儿童甲状腺组织E_max、E_min、E_mean的参考范围,但其受年龄的影响,为进一步制定儿童甲状腺正常弹性模量参考值及诊断甲状腺疾病提供参考依据。

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关键词 ：甲状腺/影像诊断, 儿童, 弹性成像技术/方法, 影响因素分析

Abstract：【Objective】 To explore the reference range and influencing factors of real-time shear wave ultrasonic elastography (SWE) in evaluating the maximum value (E_max), minimum value (E_min) and mean value (E_mean) of Young's modulus of thyroid in healthy children. 【Methods】 A total of 314 healthy children in Hunan Children's Hospital who underwent SWE examination and recorded E_max, E_min, and E_mean were selected to compare the differences of thyroid Young's modulus of elasticity E_max, E_min, and E_mean among healthy children of different sexes, different ages, and left and right long axes. 【Results】 The thyroid Young's modulus E_max, E_min, and E_mean of 314 healthy children were (13.630±3.520) KPa, (9.160 ± 2.927) KPa and (11.189 ± 3.127) KPa, respectively. There was no significant difference in young's modulus values E_max, E_min, and E_mean of the left and right long axis thyroid of healthy children between different genders (P>0.05); The thyroid Young's modulus values E_max, E_min, and E_mean of healthy children at different ages were statistically significant (P<0.05).【Conclusion】 As a quantitative and non-invasive examination method for thyroid hardness, SWE can calculate the reference range of E_max, E_min, and E_mean in thyroid tissue of healthy children according to the collected data, but it is affected by age, which provides a reference basis for further formulating the reference value of normal modulus of elasticity of children's thyroid and diagnosing thyroid diseases.

Key words： Thyroid Gland/DG Child Elasticity Imaging Techniques/MT Root Cause Analysis

收稿日期: 2022-05-12

中图分类号:

R725.81

基金资助:湖南省卫生计生委资助课题(编号:20200149,202109020998)

通讯作者: **E-mail:duanxingxing.2007@163.com

引用本文:

杨柳, 徐香芬, 袁文芳, 陈文娟, 段星星. 实时剪切波弹性成像评估健康儿童甲状腺杨氏模量值的参考范围及其影响因素[J]. 医学临床研究, 2022, 39(9): 1322-1324.
YANG Liu, XU Xiang-fen, YUAN Wen-fang, et al. Reference Range and Influencing Factors of Young's Modulus of Thyroid in Healthy Children Assessed by Real-time Shear Wave Elastography. JOURNAL OF CLINICAL RESEARCH, 2022, 39(9): 1322-1324.

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http://journal07.magtech.org.cn/yxlcyj/CN/10.3969/j.issn.1671-7171.2022.09.012 或 http://journal07.magtech.org.cn/yxlcyj/CN/Y2022/V39/I9/1322