Abstract：【Objective】To investigate the safety and feasibility of preglottic high flow oxygen in painless gastroscopy in obese patients. 【Methods】Eighty obese patients undergoing painless gastroscopy were randomly divided into the observation group (group A) and the control group (group B), with 40 cases in each group. Group A was given preglottic high-flow oxygen (oxygen flow 8-10L/min), while group B was given traditional nasal catheter oxygen (oxygen flow 3L/min). The mean arterial pressure (MAP), heart rate (HR), respiratory rate (RR), and arterial oxygen saturation (SpO2) before anesthesia (T0), at the time of disappearance (T1), 2 minutes after the disappearance of eyelash reflexes (T2), and awake at the end of gastroscopy (T3) were compared between the two groups. Meanwhile the tongue base fall, jaw support or mask assisted ventilation , the dosage of propofol, the gastroscopy operation time and the awakening time were also compared. 【Results】 Levels of MAP, HR and RR at T0, T1, T2, and T3 between the two groups of patients were not statistically significant (P>0.05). The SpO2 levels of group A with high-flow preglottic oxygen at T1 and T2 were higher than those of group B with nasal cannula oxygen, the differences were statistically significant (P<0.05). The number of hypoxemia and jaw support in group A were 0, which were significantly lower than those in group B (6 cases of hypoxemia and 14 cases of mandibular support). The difference was statistically significant (P<0.05). There were no statistically significant differences in the total dosage of propofol, gastroscope operation time and anesthesia recovery time between the two groups (P>0.05). 【Conclusion】In the painless gastroscopy of obese patients, preglottic high-flow oxygen can significantly improve the SpO2 level and improve the safety of anesthesia, which is worthy of clinical promotion.
王启明, 董丽露, 罗成. 声门前高流量给氧在肥胖患者无痛胃镜检查中的应用[J]. 医学临床研究, 2022, 39(2): 215-218.
WANG Qi-ming, DONG Li-lu, LUO Cheng. Application of High Flow Preglottic Oxygen Therapy in Painless Gastroscopy in Obese Patients. JOURNAL OF CLINICAL RESEARCH, 2022, 39(2): 215-218.
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2022, Vol. 39 
