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医学临床研究  2022, Vol. 39 Issue (1): 23-25    DOI: 10.3969/j.issn.1671-7171.2022.01.006
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术后不同液体平衡量对重度子痫前期患者预后的影响
冯力元, 王振辉**
湖南省妇幼保健院妇产科,湖南 长沙 410008
Effect of Postoperative Fluid Balance on Prognosis of Patients with Severe Preeclampsia
FENG Li-yuan, WANG Zhen-hui
Department of Obstetrics and Gynecology, The Maternal and Child Health Care Hospital of Hunan Province, Changsha Hunan 410008
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摘要 【目的】回顾性分析重度子痫前期患者术后不同液体平衡量对其预后及住院时间的影响。【方法】选择本院收治的683例重度子痫前期均行剖宫产的患者,术后前3 d均记录24 h出入水量,根据术后不同液体平衡量分为三组,A组为液体正平衡组(n=134,术后3 d内液体出入量>200 mL),B组为液体平衡组(n=189,术后3 d内液体出入量为-200~200 mL),C组为液体负平衡组(n=360,术后3 d内液体出入量≤-1000 mL)。比较术后3 d各组心率、血氧饱和度、最高收缩压、最高舒张压、脑钠肽(BNP)、尿比重以及各组住院天数,并比较产后42 d各组尿蛋白转阴率、血压和BNP恢复正常的情况。【结果】A组和B组患者的血氧饱和度均低于C组,差异有统计学意义(P<0.05),A组、B组比较差异无统计学意义(P>0.05); A组和B组患者心率、最高收缩压及最高舒张压、住院天数均高于C组,差异有统计学意义(P<0.05),A组、B组比较差异无统计学意义(P>0.05);三组的BNP水平、尿比重比较,差异均无统计学意义(均P>0.05)。产后42 d,A组尿蛋白转阴率低于C组(P<0.05),A组血压恢复正常率低于B组、C组(P<0.05),而B组和C组比较差异无统计学意义(P>0.05);三组的BNP恢复正常率(3 d内≥1000 mL)比较,差异无统计学意义(P>0.05)。【结论】重度子痫前期术后液体出入量达负平衡可以改善患者的血压,提高血氧饱和度,减少住院时间,可有效改善患者预后。
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冯力元
王振辉
关键词 先兆子痫产前诊断妊娠结局    
Abstract:【Objective】To retrospectively analyze the effects of different fluid balance on the prognosis and hospital stay of patients with severe preeclampsia. 【Methods】A total of 683 patients with severe preeclampsia who underwent cesarean section in our hospital was selected. The water inflow and outflow for 24 hours were recorded in the first 3 days after operation. They were divided into three groups according to different fluid balance after operation. Group A was positive fluid balance (n=134, fluid inflow and outflow within 3 days after operation >200 mL), and group B was fluid balance (n=189, fluid inflow and outflow within 3 days after operation -200~200 mL), Group C was the negative fluid balance group (n=360, the amount of fluid in and out within 3 days after operation was ≤-1000 mL). The heart rate, blood oxygen saturation, maximum systolic blood pressure, maximum diastolic blood pressure, brain natriuretic peptide (BNP), urinary specific gravity and the length of hospital stay in each group were compared 3 days after operation, and the negative rate of urinary protein, blood pressure and BNP return to normal 42 days after delivery were compared. 【Results】The blood oxygen saturation of the group A and the group B was lower than that of the group C (P<0.05), but there was no significant difference between the group A and the group B (P>0.05); The heart rate, maximum systolic blood pressure, maximum diastolic blood pressure and hospital stay in the group A and the group B were significantly higher than those in the group C (P<0.05), but there was no significant difference between the group A and the group B (P>0.05); There was no significant difference in BNP level and urinary specific gravity among the three groups (all P>0.05). At 42 days postpartum, the negative rate of urinary protein in group A was lower than that in the group C (P<0.05), and the return to normal rate of blood pressure in the group A was lower than that in the group B and the group C (P<0.05), but there was no significant difference between the group B and the group C (P>0.05); BNP returned to normal in the three groups, and there was no significant difference (P>0.05). 【Conclusion】The negative balance of fluid inflow and outflow after severe preeclampsia can improve the patient's blood pressure, increase the blood oxygen saturation, reduce the length of hospital stay, and effectively improve the patient's prognosis.
Key wordsPre-Eclampsia    Prenatal Diagnosis    Pregnancy Outcome
收稿日期: 2021-04-19     
中图分类号:  R714.244  
基金资助:湖南省自然科学基金(项目编号:2019JJ50297)
通讯作者: **E-mail:65556554@qq.com   
引用本文:   
冯力元, 王振辉. 术后不同液体平衡量对重度子痫前期患者预后的影响[J]. 医学临床研究, 2022, 39(1): 23-25.
FENG Li-yuan, WANG Zhen-hui. Effect of Postoperative Fluid Balance on Prognosis of Patients with Severe Preeclampsia. JOURNAL OF CLINICAL RESEARCH, 2022, 39(1): 23-25.
链接本文:  
http://journal07.magtech.org.cn/yxlcyj/CN/10.3969/j.issn.1671-7171.2022.01.006     或     http://journal07.magtech.org.cn/yxlcyj/CN/Y2022/V39/I1/23
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