Abstract：【Objective】 To explore the clinical value of spleen-preserving surgery in the treatment of splenic rupture. 【Methods】 The clinical data of 64 patients with traumatic splenic rupture admitted to our hospital from January 2014 to August 2019 were retrospectively analyzed. According to different treatment methods, they were divided into observation group (spleen repair, n=31) and control group (partial splenectomy, n=33). The operation conditions of the two groups were recorded, and the levels of CD3+ , CD4+, CD8+ T lymphocytes, serum C-reactive protein (CRP) and tumor necrosis factor-α(TNF-α) were detected before and after operation.【Results】 There was no significant difference in operation time, hospitalization time, intraoperative blood loss and anal exhaust time between the two groups (P>0.05). At 4 weeks after operation, the levels of CD3+ and CD4+ T lymphocytes in the two groups were higher than those before operation, while the level of CD8+ T lymphocytes was lower than that before operation, and the difference was statistically significant (P<0.05); The serum levels of CRP and TNF-α in the two groups were significantly higher than those before operation (P<0.05); There was no significant difference in serum CRP and TNF-α levels between the two groups at 4 weeks after operation (P>0.05). The incidence of postoperative complications was 6.45% (2/31) in the observation group and 9.09% (3/33) in the control group, with no significant difference (χ2=0.155,P=0.694>0.05).【Conclusion】 Compared with partial splenectomy, splenic repair is more helpful to improve immune function.
王卫伟, 王忠玉. 保脾性手术治疗脾破裂的临床疗效分析[J]. 医学临床研究, 2021, 38(5): 754-756.
WANG Wei-wei, WANG Zhong-yu. Clinical Analysis of Spleen Preserving Surgery in the Treatment of Splenic Rupture. JOURNAL OF CLINICAL RESEARCH, 2021, 38(5): 754-756.
2021, Vol. 38 
