Abstract：【Objective】To investigate the risk factors of perioperative ischemic stroke in patients with cerebrovascular stenosis treated by stent implantation. 【Methods】The clinical data of 160 patients with cerebrovascular stenosis treated by stent implantation in our hospital from May 2015 to may 2019 were retrospectively analyzed. According to the occurrence of perioperative ischemic stroke, they were divided into non stroke group (n=139) and stroke group (n=21). The general information, NIHSS before and after operation, the use of vasoactive drugs before and after treatment, imaging examination before and after operation, the mean value of systolic blood pressure (SBP) in the morning and afternoon 1 day before operation, and the slowest value of heart rate (HR) were recorded. Logistic multivariate analysis was used to analyze the risk factors of perioperative ischemic stroke.【Results】 Among 160 patients, 21 (13.13%) had ischemic stroke after stent implantation. There were significant differences between the two groups in average age, antiplatelet drugs before admission, calcified plaque, preoperative combined with untreated vascular stenosis, and the slowest HR < 60 beats/min (P<0.05). Increased age, calcified plaque and preoperative combined with untreated vascular stenosis were independent risk factors for perioperative ischemic stroke in patients with stent implantation cerebral vascular stenosis (P<0.001). The use of antiplatelet drugs before admission and the slowest HR value during operation were protective factors (P<0.001). 【Conclusion】The older age, calcified plaque and preoperative combined with untreated vascular stenosis are independent risk factors of perioperative ischemic stroke in patients with stent implantation cerebral vascular stenosis, and a safe surgical treatment plan should be formulated according to individual differences of patients before operation.
杜方雷, 曹宏斌. 行支架植入术治疗的脑血管狭窄患者围术期缺血性脑卒中发生的危险因素分析[J]. 医学临床研究, 2021, 38(6): 906-908.
DU Fang-lei, CAO Hong-bin. Analysis of Risk Factors of Perioperative Ischemic Stroke in Patients with Cerebrovascular Stenosis Treated by Stent Implantation. JOURNAL OF CLINICAL RESEARCH, 2021, 38(6): 906-908.
2021, Vol. 38 
