Application Value of Magnetic Resonance Diffusion Tensor Imaging in the Selection of Surgical Segments and Evaluation of Curative Effect of Multilevel Cervical Spondylotic Myelopathy
CHEN Yao-xin, LI Song-bo, LIU Xian-yin, et al
Dongguan People's Hospital/Dongguan People's Hospital affiliated to Southern Medical University, Dongguan Guangdong 523018
Abstract：【Objective】 To investigate the application value of diffusion tensor imaging (DTI) in the selection of surgical segments and the evaluation of curative effect of multilevel cervical spondylotic myelopathy.【Methods】 From February 2018 to February 2019, 30 patients with multilevel cervical spondylotic myelopathy were selected The severity of spinal stenosis was graded according to T2WI sequence standard. The apparent diffusion coefficient (ADC) and anisotropy (FA) values of each segment of spinal cord were obtained based on the results of DTI. The responsible segment of cervical spinal cord function damage was determined, and then cervical decompression surgery was performed. JOA score, NDI score and SF-36 quality of life score were recorded before operation, 6 months and 12 months after operation were recorded respectively. Post-operation X-ray film and CT were reviewed to understand the situation of internal fixation. MRI scan and DTI were reviewed at 6 and 12 months after operation, and relevant image data were collected. The changes of ADC value and FA value of spinal cord before and after operation were compared, and the correlation between ADC value and JOA score, NDI score and SF-36 quality of life score was analyzed. 【Results】 There were statistically significant differences in JOA score, NDI score, SF-36 score, ADC value and FA value before operation, 6 months after operation and 12 months after operation (P<0.05). JOA score and SF-36 score were negatively correlated with ADC value, and positively correlated with FA value (P<0.05). The NDI score was positively correlated with ADC value, and negatively correlated with FA value (P<0.05). 【Conclusion】 For patients with multilevel cervical spondylotic myelopathy, the decrease of FA value, the increase of ADC value, the gradual decrease of JOA score, the gradual increase of NDI score, and the decrease of SF-36 score of quality of life indicate that the more serious the cervical spinal cord lesion, the more serious the neurological dysfunction, and the worse the quality of life.
陈耀鑫, 黎松波, 刘先银, 黎建文, 方冠军. 磁共振弥散张量成像在多节段脊髓型颈椎病手术节段的选择和疗效评估中的应用价值[J]. 医学临床研究, 2020, 37(10): 1490-1493.
CHEN Yao-xin, LI Song-bo, LIU Xian-yin, et al. Application Value of Magnetic Resonance Diffusion Tensor Imaging in the Selection of Surgical Segments and Evaluation of Curative Effect of Multilevel Cervical Spondylotic Myelopathy. JOURNAL OF CLINICAL RESEARCH, 2020, 37(10): 1490-1493.
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2020, Vol. 37 
