医学临床研究
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医学临床研究  2020, Vol. 37 Issue (10): 1483-1486    DOI: 10.3969/j.issn.1671-7171.2020.10.013
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终末期尿毒症维持性血液透析患者运动功能的影响因素
付新萍1, 赵英2
1.山东省立第三医院血透室,山东 济南 250013;
2.山东省肿瘤防治研究院胃肠二病区,山东 济南 250000
Influencing Factors of Motor Function in Maintenance Hemodialysis Patients with End-stage Uremia
Fu Xin-ping, ZHAO Ying
Hemodialysis room, the Third Hospital of Shandong Province, Shandong Jinan 250013
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摘要 【目的】 探讨终末期尿毒症维持性血液透析(MHD)患者运动功能的影响因素。【方法】 选择2018年6至2020年6月在本院诊治的终末期尿毒症MHD患者137例,均行MHD≥6个月。终末期尿毒症患者在非透析日检测患者肌力和心肺耐力评价运动功能,根据运动功能情况分为运动功能衰退(6 min步行距离<350 m,男性握力<65 kg或女性握力<30 kg)与运动功能正常(6 min步行距离≥350 m,男性握力≥65 kg或女性握力≥30 kg)。单因素分析终末期尿毒症MHD患者运动功能的影响因素;多因素logistic回归分析终末期尿毒症MHD患者运动功能的独立危险因素。【结果】 终末期尿毒症MHD患者137例中运动功能衰退65例,发生率为47.44%。运动功能衰退组双下肢蹬踏力和握力低于运动功能正常组,且6 min步行距离短于运动功能正常组(P<0.05)。单因素分析结果显示:运动功能衰退组与运动功能正常组在性别、体质量指数(BMI)、原发疾病、肌酐(SCr)、尿素氮(BUN)、高密度脂蛋白胆固醇(HDL-C)、低密度脂蛋白胆固醇(LDL-C)、总胆固醇(TC)水平方面比较差异无统计学意义(P>0.05);年龄、透析时间、血红蛋白和合并糖尿病等比较差异具有统计学意义(P<0.05)。多因素logistic回归分析显示:年龄、透析时间、血红蛋白和合并糖尿病为影响运动功能的独立危险因素。【结论】 终末期尿毒症MHD患者运动功能受多因素影响,其中年龄、透析时间、血红蛋白和合并糖尿病为其独立危险因素,为改善患者运动功能状态,需采取合理有效的运动方法。
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付新萍
赵英
关键词 尿毒症肾透析    
Abstract【Objective】 To investigate the influencing factors of motor function in patients with end-stage uremic maintenance hemodialysis (MHD). 【Methods】 From June 2018 to June 2020, 137 MHD patients with end-stage uremia in our hospital were selected. All patients had MHD ≥ 6 months. Muscle strength and cardiopulmonary endurance were measured in patients with end-stage uremia on non dialysis days to evaluate motor function. According to the motor function, the patients were divided into motor function decline (6 min walking distance < 350 m, male grip strength < 65 kg or female grip strength < 30 kg) and normal motor function (6 min walking distance ≥ 350 m, male grip strength ≥ 65 kg or female grip strength ≥ 30 kg were regarded as normal motor function). Univariate analysis of end-stage uremic MHD patients with motor function influencing factors; multivariate logistic regression analysis of end-stage uremic MHD patients with independent risk factors of motor function. 【Results】 Among 137 MHD patients with end-stage uremia, 65 cases had motor dysfunction, the incidence was 47.44%. The pedaling force and grip strength of both lower limbs in the motor function decline group were lower than those in the normal motor function group, and the 6-minute walking distance was shorter than that in the normal motor function group (P<0.05). The results of univariate analysis showed that there were no significant differences in gender, body mass index (BMI), primary disease, SCr,BUN, HDL-C, LDL-C and TC between the two groups (P>0.05); age, dialysis time and blood pressure were not significantly different between the two groups (P>0.05) There were significant differences in erythrocyte protein and diabetes mellitus (P<0.05). Multivariate logistic regression analysis showed that age, dialysis time, hemoglobin and diabetes mellitus were independent risk factors of exercise function.【Conclusion】 The motor function of MHD patients with end-stage uremia is affected by many factors, including age, dialysis time, hemoglobin and diabetes mellitus as its independent risk factors. In order to improve the motor function of patients, it is necessary to take reasonable and effective exercise methods.
Key wordsUremia    Renal Dialysis
收稿日期: 2020-09-14     
PACS:  R69  
基金资助:山东省医药卫生科技发展计划项目(2018WS285)
引用本文:   
付新萍, 赵英. 终末期尿毒症维持性血液透析患者运动功能的影响因素[J]. 医学临床研究, 2020, 37(10): 1483-1486.
Fu Xin-ping, ZHAO Ying. Influencing Factors of Motor Function in Maintenance Hemodialysis Patients with End-stage Uremia. JOURNAL OF CLINICAL RESEARCH, 2020, 37(10): 1483-1486.
链接本文:  
http://journal07.magtech.org.cn/yxlcyj/CN/10.3969/j.issn.1671-7171.2020.10.013     或     http://journal07.magtech.org.cn/yxlcyj/CN/Y2020/V37/I10/1483
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