Abstract:【Objective】 To investigate the influencing factors of motor function in patients with end-stage uremic maintenance hemodialysis (MHD). 【Methods】 From June 2018 to June 2020, 137 MHD patients with end-stage uremia in our hospital were selected. All patients had MHD ≥ 6 months. Muscle strength and cardiopulmonary endurance were measured in patients with end-stage uremia on non dialysis days to evaluate motor function. According to the motor function, the patients were divided into motor function decline (6 min walking distance < 350 m, male grip strength < 65 kg or female grip strength < 30 kg) and normal motor function (6 min walking distance ≥ 350 m, male grip strength ≥ 65 kg or female grip strength ≥ 30 kg were regarded as normal motor function). Univariate analysis of end-stage uremic MHD patients with motor function influencing factors; multivariate logistic regression analysis of end-stage uremic MHD patients with independent risk factors of motor function. 【Results】 Among 137 MHD patients with end-stage uremia, 65 cases had motor dysfunction, the incidence was 47.44%. The pedaling force and grip strength of both lower limbs in the motor function decline group were lower than those in the normal motor function group, and the 6-minute walking distance was shorter than that in the normal motor function group (P<0.05). The results of univariate analysis showed that there were no significant differences in gender, body mass index (BMI), primary disease, SCr,BUN, HDL-C, LDL-C and TC between the two groups (P>0.05); age, dialysis time and blood pressure were not significantly different between the two groups (P>0.05) There were significant differences in erythrocyte protein and diabetes mellitus (P<0.05). Multivariate logistic regression analysis showed that age, dialysis time, hemoglobin and diabetes mellitus were independent risk factors of exercise function.【Conclusion】 The motor function of MHD patients with end-stage uremia is affected by many factors, including age, dialysis time, hemoglobin and diabetes mellitus as its independent risk factors. In order to improve the motor function of patients, it is necessary to take reasonable and effective exercise methods.
付新萍, 赵英. 终末期尿毒症维持性血液透析患者运动功能的影响因素[J]. 医学临床研究, 2020, 37(10): 1483-1486.
Fu Xin-ping, ZHAO Ying. Influencing Factors of Motor Function in Maintenance Hemodialysis Patients with End-stage Uremia. JOURNAL OF CLINICAL RESEARCH, 2020, 37(10): 1483-1486.