医学临床研究
  2025年4月6日 星期日           首 页    |    期刊简介    |    编委会    |    投稿指南    |    期刊订阅    |    广告合作    |    留言板    |    联系我们    |    English
医学临床研究  2020, Vol. 37 Issue (2): 255-258    DOI: 10.3969/j.issn.1671-7171.2020.02.029
  论著 本期目录 | 过刊浏览 | 高级检索 |
糖尿病视网膜病变黄斑区血流密度和黄斑中心凹无血管区面积的变化及其意义
王茜, 陈冰
青海省西宁市第一人民医院眼科,青海 西宁 810000
Change of Blood Flow Density and No-vessel Area in Macular Fovea in dDiabetic Retinopathy and its Significance
WANG Qian, CHEN Bing
Department of Ophthalmology, Xining First People's Hospital, Xining, 810000, Qinghai province, China
全文: PDF (0 KB)   HTML (1 KB) 
输出: BibTeX | EndNote (RIS)      
摘要 【目的】探讨糖尿病视网膜病变(diabetic retinopathy,DR)黄斑区血流密度(macular vascular density,MVD)和黄斑中心凹无血管区(foveal avascular zone,FAZ)面积的变化及其意义。【方法】选取2015年2月至2017年2月在本院就诊的74例糖尿病患者(DM组)及同期40例健康查体者(CON)的临床资料,糖尿病患者根据眼科检查分为无DR组(No-DR组)、非增殖性糖尿病DR组(NPDR组)和增殖性糖尿病DR组(PDR组)。光学相干断层扫描血管成像技术(optical coherence tomography angiography,OCTA)检测各组MVD和FAZ横径、竖径和面积并比较。【结果】DM组共有135只眼,其中No-DR组共71只,NPDR组共53只眼,PDR组共11只眼,正常CON共80只眼。PDR组、NPDR组在表层、内层视网膜及脉络膜毛细血管层的MVD均明显低于CON(均P<0.05)。No-DR组在表层、内层视网膜的MVD均明显低于CON(均P<0.05);PDR组、NPDR组在表层、内层视网膜及脉络膜毛细血管层MVD明显低于No-DR组(均P<0.05)。与CON相比, PDR组FAZ竖径、横径及面积明显较大(均P<0.05);No-DR组、NPDR组FAZ面积明显较大(P=0.000),而FAZ竖径、横径无显著差别(均P>0.05)。【结论】DR患者FAZ面积扩大及MVD降低,对早期诊断DR具有重要临床价值。
服务
把本文推荐给朋友
加入我的书架
加入引用管理器
E-mail Alert
RSS
作者相关文章
王茜
陈冰
关键词 糖尿病视网膜病变局部血流体层摄影术,光学相干    
Abstract【Objective】To investigate the changes of macular vascular density (MVD) and foveal avascular zone (FAZ) in diabetic retinopathy (DR).【Methods】From February 2015 to February 2017, 74 diabetic patients (DM group) and 40 healthy controls (CON) were selected. Diabetic patients were divided into no DR group, NPDR group and PDR group. The transverse, vertical and area of MVD and FAZ were measured and compared by optical coherence tomography (OCTA).【Results】There were 135 eyes in the DM group, 71 in the no-DR group, 53 in the NPDR group, 11 in the PDR group and 80 in the normal CON group. MVD of the PDR group and the NPDR group was significantly lower than that of con group (P<0.05).The MVD of the surface and inner retinas of the No-DR group was significantly lower than that of the CON (all P<0.05), and that of the PDR group and the NPD group was significantly lower than that of the No-DR group (all P<0.05). Compared with the CON, the vertical diameter, horizontal diameter and area of FAZ in the PDR group were significantly larger (P<0.05); the area of FAZ in the no-DR group and the NPDR group was significantly larger (P=0.000), but there was no significant difference in the vertical diameter and horizontal diameter of FAZ (P>0.05).【Conclusion】The expansion of FAZ area and the decrease of MVD in DR patients have important clinical value for early diagnosis of DR.
Key wordsDiabetic Retinopathy    Regional Blood Flow    Tomography,Optical Coherence
收稿日期: 2018-09-18     
PACS:  R587.26  
引用本文:   
王茜, 陈冰. 糖尿病视网膜病变黄斑区血流密度和黄斑中心凹无血管区面积的变化及其意义[J]. 医学临床研究, 2020, 37(2): 255-258.
WANG Qian, CHEN Bing. Change of Blood Flow Density and No-vessel Area in Macular Fovea in dDiabetic Retinopathy and its Significance. JOURNAL OF CLINICAL RESEARCH, 2020, 37(2): 255-258.
链接本文:  
http://journal07.magtech.org.cn/yxlcyj/CN/10.3969/j.issn.1671-7171.2020.02.029     或     http://journal07.magtech.org.cn/yxlcyj/CN/Y2020/V37/I2/255
版权所有 © 2013 医学临床研究杂志社  湘ICP备13012052号-1
办公地址:湖南省长沙市芙蓉区新军路43号煤炭大院主办公楼6楼621、623、632、636室 邮编:410011 电话(传真):0731-84824007 E-mail:jcr_cs.hn@vip.163.com
技术支持:北京玛格泰克科技发展有限公司 技术支持:support@magtech.com.cn