医学临床研究
  2025年4月6日 星期日           首 页    |    期刊简介    |    编委会    |    投稿指南    |    期刊订阅    |    广告合作    |    留言板    |    联系我们    |    English
医学临床研究  2019, Vol. 36 Issue (10): 1915-1917    DOI: 10.3969/j.issn.1671-7171.2019.10.014
  论著 本期目录 | 过刊浏览 | 高级检索 |
晚发型重度子痫前期患者外周血Treg/Th17细胞亚群含量和妊娠结局分析
李燕君, 俄洛吉
青海省人民医院产科,青海 西宁 810001
Analysis of Relationship between Treg/Th17 Cell Subsets in Peripheral Blood and Pregnancy Outcomes in Patients with Late Severe Preeclampsia
LI Yan-jun, E Luo-ji
Department of Obstetrics,Qinghai Provincial People's Hospital, 810001
全文: PDF (0 KB)   HTML (1 KB) 
输出: BibTeX | EndNote (RIS)      
摘要 目的】探讨晚发型重度子痫前期患者外周血Treg/Th17细胞亚群含量和妊娠结局的关系。【方法】选取120例晚发型重度子痫前期患者作为观察组,另外选取同期入院行产前检查的正常晚期妊娠妇女40例作为对照组。采用流式细胞术检测两组外周血Treg、Th17细胞含量,分析两组妊娠结局与Treg/Th17细胞亚群的关系。【结果】观察组外周血Th17细胞水平显著高于对照组, Treg细胞水平显著低于对照组(P<0.05)。观察组剖宫产率、子痫发生率、低体质量儿比例显著高于对照组(P<0.05),自然分娩率显著低于对照组(P<0.05)。【结论】晚发型重度子痫前期患者外周血存在Treg、Th17细胞亚群紊乱,其剖宫产率、低体质量儿比例、子痫发生率显著高于正常妊娠妇女。
服务
把本文推荐给朋友
加入我的书架
加入引用管理器
E-mail Alert
RSS
作者相关文章
李燕君
俄洛吉
关键词 先兆子痫/诊断Th17细胞妊娠结局    
Abstract:【Objective】To investigate the relationship between Treg/Th17 cell subsets and pregnancy outcome in patients with later severe preeclampsia. 【Methods】A total of 120 patients with severe late preeclampsia were collected as the observation group and 40 normal late pregnant women with prenatal examination in the same period were selected as the control group. The contents of Treg and Th17 cells in peripheral blood were measured by flow cytometry. The results of pregnancy outcome, neonatal outcome and complications in the two groups were compared. 【Results】The level of Th17 cells in the peripheral blood of the observation group was significantly higher than that of the control group, and the level of Treg cells was significantly lower than that of the control group (P<0.05). The cesarean section rate in the observation group was significantly higher than that in the control group, and the natural delivery rate was significantly lower than that in the control group (P<0.05). The proportion of low birth weight infants in the observation group was significantly higher than that in the control group (P<0.05). The incidence of eclampsia in the observation group was significantly higher than that in the control group (P<0.05). 【Conclusion】 There are disorders of Treg and Th17 cell subsets in the peripheral blood of severe later preeclampsia patients. The cesarean section rate, the proportion of low birth weight infants and the incidence of eclampsia are significantly higher than those in normal pregnant women.
Key wordsPre-Eclampsia/DI    Th17 Cells    Pregnancy Outcome
收稿日期: 2019-05-05     
PACS:  R714.244  
引用本文:   
李燕君, 俄洛吉. 晚发型重度子痫前期患者外周血Treg/Th17细胞亚群含量和妊娠结局分析[J]. 医学临床研究, 2019, 36(10): 1915-1917.
LI Yan-jun, E Luo-ji. Analysis of Relationship between Treg/Th17 Cell Subsets in Peripheral Blood and Pregnancy Outcomes in Patients with Late Severe Preeclampsia. JOURNAL OF CLINICAL RESEARCH, 2019, 36(10): 1915-1917.
链接本文:  
http://journal07.magtech.org.cn/yxlcyj/CN/10.3969/j.issn.1671-7171.2019.10.014     或     http://journal07.magtech.org.cn/yxlcyj/CN/Y2019/V36/I10/1915
版权所有 © 2013 医学临床研究杂志社  湘ICP备13012052号-1
办公地址:湖南省长沙市芙蓉区新军路43号煤炭大院主办公楼6楼621、623、632、636室 邮编:410011 电话(传真):0731-84824007 E-mail:jcr_cs.hn@vip.163.com
技术支持:北京玛格泰克科技发展有限公司 技术支持:support@magtech.com.cn