Analysis of Recurrence Rate of Gestational Diabetes Mellitus, Risk Factors for Recurrence and Maternal and Infant Prognosis of Recurrent Gestational Diabetes Mellitus
LIU Mei, WANG Xing-he, ZHANG Ming-cheng, et al
Department of Medicine, the Dongguan Maternal and Child Health Hospital, Guangdong Province, Dongguan 523000
Abstract：【Objective】To study the recurrence rate, risk factors of recurrence of gestational diabetes mellitus(GDM) and the prognosis of mother and infant in recurrent GDM. 【Methods】A total of 142 pregnant women who had ever had GDM from January to December 2016, who had been examined in our hospital's obstetrical clinic were followed up. At the time of OGTT, 76 patients with recurrent GDM entered the observation group and 66 pregnant women without diabetes mellitus entered the negative control group. At the same time, 80 patients with primary GDM were randomly selected as the positive control group. The three groups were followed up to 6 months postpartum according to the clinical follow-up table to observe and calculate the prognosis of mother and infant and to screen the risk factors for recurrence of GDM. 【Results】The recurrence rate of GDM was 54.2%. Compared the observation group with the negative control group, there were significant differences between the two groups in fasting blood glucose(FBG), 2 hours postprandial blood glucose (2hPG), the pre-pregnancy body mass index(BMI) , the complications during pregnancy and delivery and neonatal complications. Compared with the positive control group, there were differences between the observation group and the positive control group in the number of births, the complications of some pregnant and delivery women, the complications of some newborns; the differences in the results of postpartum OGTT were significant. Risk factors for relapse included BMI before this pregnancy, the FGP and 2 hPG at last pregnancy.【Conclusion】The higher the FPG and 2hPG in the last pregnancy, the heavier the weight of the pregnancy, the more likely the GDM will recur.The higher the FPG and 2hPG in the last pregnancy, the heavier the weight of the pregnancy, the more likely the GDM will recur. Infants of patients with recurrent GDM are more likely to develop hypoglycemia and unobturated foramen ovale than those with primary GDM, and the risk of long term postpartum diabetes is increased.
刘眉, 王兴和, 张铭承, 黎伟文. 妊娠期糖尿病的复发率、复发的危险因素及复发性妊娠期糖尿病母婴预后的分析[J]. 医学临床研究, 2018, 35(5): 845-848.
LIU Mei, WANG Xing-he, ZHANG Ming-cheng, et al. Analysis of Recurrence Rate of Gestational Diabetes Mellitus, Risk Factors for Recurrence and Maternal and Infant Prognosis of Recurrent Gestational Diabetes Mellitus. JOURNAL OF CLINICAL RESEARCH, 2018, 35(5): 845-848.
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2018, Vol. 35 
