Abstract：【Objective】To investigate the effect of tubeless percutaneous nephrolithotomy (PCNL) in the treatment of incarcerated upper ureteral calculi and its influence on serum inflammatory factors. 【Methods】The clinical data of 120 patients with incarcerated upper ureteral calculi in our hospital were selected and divided into observation group (tubeless PCNL operation) and control group (retroperitoneal laparoscopic operation), 60 cases each. The operation time, intraoperative bleeding volume, hospital stay, duration of hematuria and stone clearance rate, serum levels of interleukin-2 (IL-2), interleukin-6 (IL-6), prostaglandin E2 (PGE2) and tumor necrosis factor- α (TNF-α) before and after operation were compared between the two groups. 【Results】The operation time, intraoperative bleeding volume and hospitalization time of the observation group were lower than those of the control group, and the duration of naked hematuria after operation was longer than that of the control group (P<0.05). The stone clearance rate of the control group was 100.00% (60/60), while that of the observation group was 93.33% (56/60) and 98.33% (59/60), respectively, with no significant difference (P>0.05). The incidence of postoperative complications in the observation group was 5.00% (3/60) lower than that in the control group 16.67% (10/60). The difference was statistically significant (χ2=4.227,P=0.04<0.05). 24 hours after operation, the serum levels of IL-6, PGE2 and TNF-alpha in the observation group were lower than those in the control group (P<0.05), and the serum levels of IL-2 were higher than those in the control group (P<0.05).【Conclusion】The stone clearance rate of tubeless PCNL in the treatment of incarcerated upper ureter calculi is not significantly different from that of retrolaparoscopic surgery, but the trauma is smaller, the postoperative recovery is faster, the complications are fewer, and the degree of inflammatory reaction is less.
符仕宝, 肖劲逐, 何书明, 陈宁, 张善斌, 车宪平, 徐磊. 无管化PCNL治疗嵌顿性输尿管上段结石的效果及对患者血清炎症因子的影响[J]. 医学临床研究, 2019, 36(8): 1466-1468.
FU Shi-bao, XIAO Jing-zhu, HE Shu-ming, et al. Effect of tubeless PCNL in the Treatment of Incarcerated Upper Ureteral Calculi and its Influence on Serum Inflammatory Factors. JOURNAL OF CLINICAL RESEARCH, 2019, 36(8): 1466-1468.
2019, Vol. 36 
