Abstract：【Objective】 To compare the perioperative related indicators and short-term efficacy of percutaneous nephrolithotomy (PCNL) and ureteroscopy (RIRS) in the treatment of isolated kidney stones. 【Methods】 A total of 96 patients with isolated kidney stones were random divided into group A(PCNL) and group B(RIRS),with 48 cases in each group. Levels of serum interleukin 6 (IL-6), C-reactive protein (CRP), white blood cell count (WBC), and cortisol (Cor) in the morning before surgery and on the 1th day after surgery were detected. The procedure of operation was monitored. The VAS pain scores of resting state and active state at different time points after surgery, primary stone clearance rate, total clearance rate, and total incidence of complications were compared between two groups. 【Results】 The operation time of group A was shorter than that of B group (P<0.05), while the intraoper-ative blood loss, gastrointestinal function recovery time and hospitalization time were higher than those in B group (P<0.05). The levels of serum IL-6, CRP, WBC and Cor in group B were lower than those in group A (P<0.05). The VAS scores of resting state and active state in the group B at 1d, 2d and3d after surgery were lower than those in the A group (P<0.05). The one-time primary stone clearance rate , total clearance rate and the total incidence of complications in group A were 81.25%, 93.75% and18.75%, respectively, which were not significantly different in comparison with those in group B, which were 72.92%、85.42% and 20.83%, respectively (P>0.05). 【Conclusion】 RIRS can achieve the equivalent overall effect of PCNL; however, RIRS has less intraoperative bleeding , shorter hospital stay, and reduced pain and inflammation. It can be used as a preferred treatment under the premise of grasping the surgical indications.
尹宁, 韩平, 李永洪, 陈玉雄. PCNL、RIRS治疗孤立肾结石围术期相关指标及近期疗效比较[J]. 医学临床研究, 2018, 35(8): 1527-1529.
YiNing, HANPing, LIYong-hong. Observation of Perioperative Related Indicators and Short-term Curative Effect of PCNL and RIRS in the Treatment of Isolated Kidney Stone. JOURNAL OF CLINICAL RESEARCH, 2018, 35(8): 1527-1529.
[1] 杨春生,梁磊,孟繁林,等.输尿管软镜碎石术与微创经皮肾镜碎石术治疗孤立肾结石对比观察[J].山东医药,2015,55(19):48-50. [2] Martin F, Hoarau N, Lebdai S, et al. Impact of lower pole calculi in patients undergoing retrograde intenal surgery[J]. J Endourol,2014,28(2):141-145. [3] Turkan S, Irk lata L, Ekmek ioglu O, et al. The case study in the applicability of the improvements in the treatment of urinary system stone diseases in Anatolia: the last ten years with the sample of Western Black Sea region[J]. Turk J Urol,2015,41(3):138-142. [4] Koopman SG, Fuchs G. Management of stones associated with intrarenal stenosis: infundibular stenosis and caliceal diverticulum[J].J Endourol,2013,27(12):1546-1550. [5] 梁福律,范先明,郭昭建,等.输尿管软镜碎石术与经皮肾镜取石术治疗2~2.5cm肾下盏结石疗效对比[J].现代泌尿外科杂志,2015,20(7):489-492.3. [6] 廖国栋,俞蔚文,章越龙,等.超微经皮肾镜取石术在治疗肾及输尿管上段2cm结石中的应用(附52例报告)[J].临床泌尿外科杂志,2016,31(7):590-592. [7] 曾国华,赵志健,钟文,等.经皮肾镜取石术联合二期输尿管软镜手术治疗孤立肾复杂性结石的疗效研究[J].中华泌尿外科杂志,2013,34(4):268-271. [8] 羊涛,庞翔.腹腔镜联合纤维胆道镜在治疗孤立肾结石中的应用[J].广东医学,2015,36(17):2767. [9] 林海利,郑周达,杨明根,等.经皮肾镜与输尿管软镜在孤立肾结石的应用比较[J].中国微创外科杂志,2016,16(4):301-303,307. [10] 冯勇,陈文章,毛会峰,等.经皮肾镜碎石取石术与输尿管软镜碎石术治疗孤立肾肾结石的临床特点及疗效分析[J].临床医学研究与实践,2017,2(2):1-3.
2018, Vol. 35 
