Abstract:【Objective】To compare the effects of butorphanol and oxycodone in patient-controlled intravenous analgesia after transurethral ureteroscopic lithotripsy (URL) .【Methods】Two hundred and fourteen patients undergoing URL were divided into butorphanol group (group A, n=107) and oxycodone group (group B, n=107) according to the different anestheticS.The analgesic effects were compared between the two groups.【Results】The excellent rate of anesthesia, operation time and duration of anesthesia showed no statistically significant difference between the two groups (P>0.05) . 3h, 6h, 12h and 24h after postoperative patient-controlled intravenous analgesia, the pain score of the group B was significantly lower than that of the group A, the sedation score was significantly higher than that of group A, and the difference was significant (P<0.05) . The anesthetic consumption, score of Post Operative Nausea And Vomitting (PONV) of the group B were significantly less or lower than those of the group A (P<0.05) . The anesthesia satisfaction of B group was 93.46% while of A group was 87.85% (P>0.05) . The anesthesia satisfaction of the group B was 93.46%, higher than that of the group A (87.85%) (P>0.05) ; the incidence of adverse reactions in the group A was 14.02% while that in the group B was 5.61% (P<0.05) .【Conclusion】General anesthesia effects of butorphanol and oxycodone for URL anesthesia are similar, but oxycodone has a relatively small amount and good analgesic effect with less adverse reaction, and is more suitable than butorphanol for URL intrathecal anesthesia.
齐超,孙小可,毕艳敏,陈鑫,刘占坡. 布托啡诺与羟考酮用于经尿道输尿管镜碎石取石术后自控静脉镇痛的效果比较[J]. 医学临床研究, 2017, 34(11): 2127-2129.
QI Chao, SUN Xiao-ke,BI Yan-min, et al. Comparison of Butorphanol and Oxycodone for Patient-controlled Intravenous Analgesia Effect after Transurethral Ureteroscopic Lithotripsy. JOURNAL OF CLINICAL RESEARCH, 2017, 34(11): 2127-2129.