医学临床研究
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医学临床研究  2019, Vol. 36 Issue (7): 1259-1261    DOI: 10.3969/j.issn.1671-7171.2019.07.004
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喉罩通气联合肋间神经阻滞麻醉在乳腺癌改良根治术中的效果分析
李艳, 黄亚琼
中国人民解放军联勤保障部队第940医院麻醉手术科,甘肃 兰州 730050
Effect of Laryngeal Mask Ventilation Combined with Intercostal Nerve Block Anesthesia in Modified Radical Mastectomy for Breast Cancer
LI Yan, HUANG Ya-qiong
People's Liberation Army Joint Support Force 940 Hospital 730050
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摘要 【目的】探讨喉罩通气联合肋间神经阻滞麻醉在乳腺癌改良根治术患者中的麻醉效果。【方法】乳腺癌根治术患者74例随机分为两组,每组37例。对照组给予喉罩全麻,观察组采用喉罩通气联合肋间神经阻滞麻醉。比较两组麻醉诱导前(T1)、切皮时(T2)、切皮后1 h(T3)及拔除喉罩5 min(T4)时血流动力学、应激反应指标变化及麻醉安全性。【结果】观察组T3、T4时收缩压(SBP)及心率(HR)水平均低于对照组(P<0.05);观察组四个时间点SBP、HR相比较差异均无显著性(P>0.05);对照组T3、T4时间点SBP、HR均高于T1、T2时间点(P<0.05);观察组T2、T3、T4时皮质醇(Cor)及血管紧张素-Ⅱ(Ang-Ⅱ)水平 均低于对照组(P<0.05);观察组T4时间点Ang-Ⅱ水平高于T1时(P<0.05);对照组T2、T3、T4时Cor、Ang-Ⅱ水平高于T1时间点(P<0.05)。两组围术期不良反应发生率相比较差异均无显著性(P>0.05)。【结论】喉罩通气联合肋间神经阻滞麻醉用于乳腺癌改良根治术对术中血流动力学影响较小,有助于降低患者围术期应激反应,麻醉安全性较高,值得推广应用。
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李艳
黄亚琼
关键词 乳腺肿瘤/外科学乳房切除术改良根治性神经传导阻滞/方法    
Abstract【Objective】To investigate the anesthetic effect of laryngeal mask ventilation combined with intercostal nerve block anesthesia in patients undergoing modified radical mastectomy for breast cancer.【Methods】Seventy-four patients with radical mastectomy were randomly divided into two groups, 37 in each group. The control group was given laryngeal mask general anesthesia, while the observation group was given laryngeal mask ventilation combined with intercostal nerve block anesthesia. The changes of hemodynamics, stress response index and anesthesia safety before induction of anesthesia (T1), during skin incision (T2), 1 hour after skin incision (T3) and 5 minutes after removal of laryngeal mask (T4) were compared between the two groups.【Results】Systolic blood pressure (SBP) and heart rate (HR) at T3 and T4 in the observation group were lower than those in the control group (P<0.05); there was no significant difference in SBP and HR at four time points in the observation group (P>0.05); SBP and HR at T3 and T4 time points in the control group were higher than those at T1 and T2 time points (P<0.05). Cor and Ang-Ⅱ levels at T2, T3 and T4 in the observation group were lower than those in the control group (P<0.05); Ang-Ⅱ levels at T4 in the observation group were higher than those at T1 (P<0.05); Cor and Ang-Ⅱ levels at T2, T3 and T4 in the control group were higher than those at T1 (P<0.05). There was no significant difference in the incidence of perioperative adverse reactions between the two groups (P>0.05).【Conclusion】Laryngeal mask ventilation combined with intercostal nerve block anesthesia for modified radical mastectomy of breast cancer has less influence on intraoperative hemodynamics, which is helpful to reduce perioperative stress response of patients, and has high anesthesia safety. It is worth popularizing and applying.
Key wordsBreast Neoplasms/SU    Mastectomy, Modified Radical    Nerve Block/ME
收稿日期: 2019-01-18     
PACS:  R737.9  
通讯作者: E-mail:41972447@qq.com   
引用本文:   
李艳, 黄亚琼. 喉罩通气联合肋间神经阻滞麻醉在乳腺癌改良根治术中的效果分析[J]. 医学临床研究, 2019, 36(7): 1259-1261.
LI Yan, HUANG Ya-qiong. Effect of Laryngeal Mask Ventilation Combined with Intercostal Nerve Block Anesthesia in Modified Radical Mastectomy for Breast Cancer. JOURNAL OF CLINICAL RESEARCH, 2019, 36(7): 1259-1261.
链接本文:  
http://journal07.magtech.org.cn/yxlcyj/CN/10.3969/j.issn.1671-7171.2019.07.004     或     http://journal07.magtech.org.cn/yxlcyj/CN/Y2019/V36/I7/1259
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