医学临床研究
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医学临床研究  2019, Vol. 36 Issue (5): 909-910    DOI: 10.3969/j.issn.1671-7171.2019.05.025
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维D钙咀嚼片预防特发性良性阵发性位置性眩晕复发的研究
姚玉芳, 祁晓媛, 张福波, 芮汉臣, 杨潮萍
沧州市中心医院神经内科,河北 沧州 061000
Preventive effect of vitamin D calcium chewable tablets on relapse of idiopathic benign paroxysmal positional vertigo
YAO Yu-fang, QI Xiao-yuan, ZHANG Fu-bo, et al
Medical Neurology ,Cangzhou Central Hospital, Cangzhou Hebei, 061000 China
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摘要 【目的】探讨维D钙咀嚼片预防特发性良性阵发性位置性眩晕(BPPV)复发的效果。【方法】选择2015年12月至2017年12月于本院神经内四科眩晕门诊及病房诊断为特发性BPPV的患者138例为研究对象,随机分为观察组和对照组各69例,两组都给予手法复位达到临床治愈,观察组给予维D钙咀嚼片(迪巧)750 mg,每日1次,口服;对照组给予安慰剂口服。两组BPPV患者均随访1年,每4个月随访1次,记录期间复发次数。【结果】随访1年后,观察组67例患者,复发率为11.9%(8/67);对照组68例患者,复发率为27.9%(18/68),观察组复发率显著低于对照组,差异有统计学意义 (P<0.05)。【结论】维D钙咀嚼片可显著降低特发性BPPV的复发率。
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关键词 良性阵发性位置性眩晕/药物疗法维生素D    
Abstract【Objective】To explore whether vitamin D calcium chewable tablets can prevent the recurrence of idiopathic benign paroxysmal positional vertigo (BPPV). 【Methods】From December 2015 to December 2017, 138 patients with idiopathic BPPV were randomly divided into the observation group and the control group, 69 cases in each group. Both groups were treated with manual reduction to achieve clinical cure. The observation group was treated with vitamin D calcium chewable tablets (Diqiao) 750 mg, once a day, orally. The control group was given placebo orally. BPPV patients in both groups were followed up for 1 year, once every 4 months, and the recurrence times were recorded.【Results】After one year of follow-up, 67 patients in the observation group had a recurrence rate of 11.9% (8/67) and 68 patients in the control group had a recurrence rate of 27.9% (18/68). The recurrence rate in the observation group was significantly lower than that in the control group (P<0.05). 【Conclusion】 Vitamin D calcium chewable tablets can significantly reduce the recurrence rate of idiopathic BPPV.
Key wordsBenign Paroxysmal Positional Vertigo/DT    Vitamin D
收稿日期: 2018-10-08     
PACS:  R441.2  
基金资助:沧州市重点研发计划指导项目(183302015)
引用本文:   
姚玉芳, 祁晓媛, 张福波, 芮汉臣, 杨潮萍. 维D钙咀嚼片预防特发性良性阵发性位置性眩晕复发的研究[J]. 医学临床研究, 2019, 36(5): 909-910.
YAO Yu-fang, QI Xiao-yuan, ZHANG Fu-bo, et al. Preventive effect of vitamin D calcium chewable tablets on relapse of idiopathic benign paroxysmal positional vertigo. JOURNAL OF CLINICAL RESEARCH, 2019, 36(5): 909-910.
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http://journal07.magtech.org.cn/yxlcyj/CN/10.3969/j.issn.1671-7171.2019.05.025     或     http://journal07.magtech.org.cn/yxlcyj/CN/Y2019/V36/I5/909
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