Abstract：【Objective】To investigate the effect of Kuntai capsule combined with complex packing estradiol(Fenmotong) in the treatment of perimenopausal syndrome.【Methods】A total of 146 perimenopausal patients who were treated in our hospital from October 2016 to October 2017 were randomly divided into control group and observation group. Each group had 73 cases. The control group was given complex packing estradiol cycle sequential treatment. The observation group was given Kuntai Capsule on the basis of the control group. The clinical efficacy, ovarian function, quality of life and adverse drug reactions before and after treatment were compared between the two groups.【Results】There was no significant difference in FSH, AFC, LH, E2, MENQOL and clinical symptom score between the two groups before treatment (P>0.05); after treatment, the improvement effect of FSH, AFC, LH and E2 in the observation group was significantly higher than that in the control group (P<0.05); the clinical symptom score and ENQOL score in the observation group were significantly lower than those in the control group (P<0.05). In the control group (P<0.05), the total effective rate in the observation group was significantly higher than that in the control group (P<0.05); there was no significant difference in the incidence of side effects between the two groups (P>0.05). 【Conclusion】Kuntai capsule combined with Fenmotong in the treatment of perimenopausal syndrome can improve the clinical symptoms and ovarian function of patients, improve the clinical efficacy and quality of life, and is relatively safe, which is worthy of clinical application.
付丽侠. 坤泰胶囊联合芬吗通治疗围绝经期综合征患者的疗效观察[J]. 医学临床研究, 2019, 36(4): 648-650.
FU Li-Xia. Observation on the Curative Effect of Kuntai Capsule Combined with Fenmotong(complex packing estradiol) in the Treatment of Perimenopausal Syndrome. JOURNAL OF CLINICAL RESEARCH, 2019, 36(4): 648-650.
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2019, Vol. 36 
