Application Effect of Whole-Course Responsibility System Intervention Combined with Early Pulmonary Rehabilitation Training in Patients with AECOPD Complicated with Respiratory Failure
JIA Yawei, JIAO Xiaoqi, LOU Zhangju
Ward 2, Department of Respiratory and Critical Care Medicine, Zhengzhou Central Hospital Affiliated to Zhengzhou University, Zhengzhou Henan 450000
Abstract：【Objective】 To investigate the application effect of whole-course responsibility system intervention combined with early pulmonary rehabilitation training in patients with acute exacerbation of chronic obstructive pulmonary disease (AECOPD) complicated with respiratory failure. 【Methods】 A total of 100 patients with AECOPD complicated with respiratory failure admitted to our hospital from January 2022 to January 2025 were selected and divided into a control group and an observation group by random number table method, with 50 cases in each group. The control group received routine intervention, while the observation group received whole-course responsibility system intervention combined with early pulmonary rehabilitation training. Pulmonary function [forced expiratory volume in one second (FEV1), forced vital capacity (FVC), FEV1/FVC], respiratory rate, exercise endurance [6-minute walking distance (6MWD)], respiratory function [St. George's Respiratory Questionnaire (SGRQ)] and quality of life [Generic Quality of Life Inventory-74 (GQOLI-74) score] were compared between the two groups. 【Results】 After intervention, FEV1, FVC and FEV1/FVC in the observation group were higher than those in the control group (P<0.05), respiratory rate was lower than that in the control group, and 6MWD was longer than that in the control group (P<0.05). Scores of respiratory symptoms, physical activity limitation and impact on daily living ability in the observation group were lower than those in the control group (P<0.05). Scores of psychological function, physical function, social function and material life in the observation group were higher than those in the control group (P<0.05). 【Conclusion】 Whole-course responsibility system intervention combined with early pulmonary rehabilitation training can significantly improve pulmonary function, exercise endurance and quality of life in patients with AECOPD complicated with respiratory failure, promote the recovery of respiratory function, and has high clinical application value.
贾亚玮, 焦晓琪, 娄张菊. 全程责任制干预联合早期肺康复训练在AECOPD合并呼吸衰竭患者中的应用效果[J]. 医学临床研究, 2026, 43(3): 391-394.
JIA Yawei, JIAO Xiaoqi, LOU Zhangju. Application Effect of Whole-Course Responsibility System Intervention Combined with Early Pulmonary Rehabilitation Training in Patients with AECOPD Complicated with Respiratory Failure. JOURNAL OF CLINICAL RESEARCH, 2026, 43(3): 391-394.
2026, Vol. 43 
