Abstract：【Objective】 To investigate the diagnostic value of fundus fluorescein angiography (FFA) combined with optical coherence tomography (OCT) in diabetic retinopathy (DR). 【Methods】 A total of 125 patients (250 eyes) with suspected DR admitted to our hospital from August 2022 to August 2024 were selected. All patients underwent FFA and OCT examinations. Clinical diagnostic results were used as the gold standard. The diagnostic value of FFA, OCT, and combined examination in DR was compared. The retinal nerve fiber layer (RNFL) thickness in patients with proliferative diabetic retinopathy (PDR) and non-proliferative diabetic retinopathy (NPDR) was also compared. 【Results】 Among the 125 patients (250 eyes), 180 eyes were clinically diagnosed with DR. FFA examination detected DR in 152 eyes, OCT examination detected DR in 156 eyes, and combined examination detected DR in 174 eyes. The sensitivity, specificity, and accuracy of combined examination for diagnosing DR were 97.14%, 96.80%, and 96.67%, respectively, all of which were superior to any single examination. The RNFL thickness in the superior, inferior, temporal, and nasal quadrants in PDR patients was thinner than that in NPDR patients (P<0.05). 【Conclusion】 FFA combined with OCT can significantly improve the sensitivity, specificity, and accuracy of DR diagnosis. The RNFL thickness in PDR patients is thinner than that in NPDR patients. Combined examination can provide important basis for early diagnosis and staging of DR.
张炳琪, 王文玲, 户秀慧. 眼底荧光血管造影联合光学相干断层扫描对糖尿病视网膜病变的诊断价值[J]. 医学临床研究, 2026, 43(2): 258-260.
ZHANG Bingqi, WANG Wenling, HU Xiuhui. Diagnostic Value of Fundus Fluorescein Angiography Combined with Optical Coherence Tomography in Diabetic Retinopathy. JOURNAL OF CLINICAL RESEARCH, 2026, 43(2): 258-260.
2026, Vol. 43 
