Efficacy of High-Frequency Repetitive Transcranial Magnetic Stimulation Combined with Neural Facilitation Techniques for Treating Cognitive Dysfunction after Stroke
ZHANG Linling1a, ZHU Yaoyao2, YAN Wenjuan1b
1a. Department of Rehabilitation Medicine,b. Department of Orthopedics, Anting Hospital, Jiading District, Shanghai 201800; 2. Department of Rehabilitation Medicine, Tongling Hospital of Traditional Chinese Medicine, Tongling Anhui 244000
Abstract：【Objective】 To investigate the efficacy of high-frequency repetitive transcranial magnetic stimulation (rTMS) combined with neural facilitation techniques in treating patients with post-stroke cognitive impairment (PSCI). 【Methods】 A total of 82 PSCI patients were randomly divided into two groups with 41 cases each. The control group received basic treatment and neural facilitation techniques. The observation group received rTMS in addition to the same interventions as the control group. Both groups underwent interventions for 8 weeks. The clinical efficacy, cerebral hemodynamics, neurotrophic factor levels, cognitive function, and quality of life before and after treatment were compared between the two groups. 【Results】 The total effective rate in the observation group was higher than that in the control group (P<0.05). After treatment, the levels of various neurotrophic factors, the mean blood flow velocity, and the peak systolic flow velocity in the middle cerebral artery of the observation group were higher than those of the control group, while the pulsatility index was lower (P<0.05). Cognitive function, memory function, and quality of life in the observation group showed significantly greater improvement compared to the control group (P<0.05). 【Conclusion】 The combination of rTMS and neural facilitation techniques can improve the cognitive abilities, cerebral hemodynamics, neurotrophic factor levels, and quality of life in PSCI patients.
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2026, Vol. 43 
