Therapeutic Effect of Low-Frequency Neuromuscular Electrical Stimulation Combined with Robot-Assisted Rehabilitation Training in Patients with Post-Stroke Hemiplegia
REN Xiaoru, PAN Yungao, MA Yanna
Department of Neurology, Nanle Zhongxing Hospital, Puyang Henan 457400
Abstract：【Objective】 To investigate the therapeutic effect of low-frequency neuromuscular electrical stimulation(NMES) combined with robot-assisted rehabilitation training in patients with post-stroke hemiplegia.【Methods】 A total of 118 patients with post-stroke hemiplegia were divided into a control group(n=62, treated with robot-assisted rehabilitation training alone) and an observation group(n=56, treated with low-frequency NMES combined with robot-assisted rehabilitation training) according to different treatment methods. The efficacy, changes in muscle tone [Modified Ashworth Scale(MAS)], neuro-electrophysiological parameters, neurological function, motor function, and quality of life before and after treatment were compared between the two groups.【Results】 The total effective rate was 94.64%(53/56) in the observation group, which was significantly higher than 83.87%(52/62) in the control group(P<0.05). After treatment, MAS scores and levels of central nervous system-specific protein S-100β in both groups were significantly lower than those before treatment, with even lower values in the observation group compared to the control group(P<0.05). Fugl-Meyer Assessment(FMA) scores, Berg Balance Scale(BBS) scores, Modified Barthel Index(MBI), sensory and motor nerve conduction velocities of the peroneal and tibial nerves, as well as levels of brain-derived neurotrophic factor and nerve growth factor, were significantly increased in both groups after treatment(P<0.05). After treatment, the above indicators in the observation group were higher than those in the observation group(P<0.05).【Conclusion】 Low-frequency NMES combined with robot-assisted rehabilitation training can effectively improve muscle tone, neuro-electrophysiological parameters, neurological and motor functions in patients with post-stroke hemiplegia, thereby enhancing treatment efficacy and improving quality of life.
任晓如, 潘运高, 马艳娜. 低频神经肌肉电刺激联合机器辅助康复训练治疗脑梗死后偏瘫患者的疗效[J]. 医学临床研究, 2025, 42(9): 1572-1575.
REN Xiaoru, PAN Yungao, MA Yanna. Therapeutic Effect of Low-Frequency Neuromuscular Electrical Stimulation Combined with Robot-Assisted Rehabilitation Training in Patients with Post-Stroke Hemiplegia. JOURNAL OF CLINICAL RESEARCH, 2025, 42(9): 1572-1575.
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2025, Vol. 42 
