Abstract:【Objective】 To investigate the effects of different position fixation methods on the determination of margins, control of positioning errors, and patient comfort during radiotherapy for head and neck tumor patients.【Methods】 A total of 256 patients with head and neck tumors undergoing radiotherapy were divided into two groups according to the fixation methods:128 patients received thermoplastic mask fixation(the control group), and 128 patients received thermoplastic mask combined with foam cushion fixation(the observation group). Positioning errors, margins, and treatment comfort were compared between the two groups.【Results】 In the observation group, positioning errors of the first and last treatments in the X-axis, Y-axis, and Z-axis directions were significantly lower than those in the control group(P<0.05). Margins in the X-axis, Y-axis, and Z-axis directions in the observation group were also significantly smaller than those in the control group(P<0.05), with greater uniformity. There was no statistically significant difference between the two groups in social, cultural, and environmental comfort scores(P>0.05). However, psychological comfort, physical comfort, and total comfort scores in the observation group were significantly higher than those in the control group(P<0.05).【Conclusion】 In radiotherapy for patients with head and neck tumors, combining thermoplastic mask with foam cushion for position fixation can significantly reduce positioning errors and margins, and enhance the comfort experience of patients throughout the treatment period.
郭璋琪, 李兵, 毛荣虎, 孙学明, 刘晓男. 头颈部肿瘤放疗中不同体位固定方式对外扩边界、摆位误差及患者舒适度的影响*[J]. 医学临床研究, 2025, 42(9): 1512-1515.
GUO Zhangqi, LI Bing, MAO Ronghu, et al. Effects of Different Position Fixation Methods on Margins, Positioning Errors, and Patient Comfort during Radiotherapy for Head and Neck Tumors. JOURNAL OF CLINICAL RESEARCH, 2025, 42(9): 1512-1515.
[1] XU Y L,CHEN G G,MAO M,et al.Causal associations between dietary factors with head and neck cancer:A two-sample Mendelian randomization study[J].Laryngoscope Investig Otolaryngol,2025,10(1):e70070.
[2] 张卓,杨敏,王东东,等. 乳腺癌术后放疗体位固定技术的摆位误差及重复性分析[J].实用临床医药杂志,2021,25(8):52-54.
[3] 田素青,孙海涛,赵田地,等. 6D治疗床辅助影像引导下放射治疗头颈部肿瘤摆位误差分析[J].北京大学学报(医学版),2024,56(6):1097-1100.
[4] 吴艳,肖杨,李恒,等. 头颈肩热塑膜联合发泡胶固定在颈胸部肿瘤放射治疗中的应用[J].中国医学装备,2022,19(10):23-27.
[5] 中国医师协会放射肿瘤治疗医师分会,中华医学会放射肿瘤治疗学分会,中国抗癌协会肿瘤放射治疗专业委员会. 中国头颈部肿瘤放射治疗指南(2021年版)[J].国际肿瘤学杂志,2022,49(2):65-72.
[6] VAN HERK M, REMEIJER P, RASCH C,et al.The probability of correct target dosage:dose-population histograms for deriving treatment margins in radiotherapy[J].Int J Radiat Oncol Biol Phys,2000,47(4):1121-1135.
[7] 王薇,程芳,吴婉英,等. 头颈部肿瘤放射治疗患者舒适状况量表的编制及信效度检验[J].中华护理杂志,2013,48(10):869-872.
[8] 贾卫娟,周军,罗灿,等. ExacTrac影像引导系统引导下不同固定方式对下肢放射治疗患者摆位误差的影响研究[J].医疗卫生装备,2024,45(3):61-65.
[9] TOSHIE I ,NANAMI H ,YOSHINORI T , et al.Evaluation of setup errors of immobilization device for radiation therapy in companion animals.[J].Open Vet,2022,12(6):929-935.
[10] 苏晖,鲍瑜,查道俊. 头颈部调强放射治疗中影响摆位误差的相关因素分析[J].临床和实验医学杂志,2024,23(21):2335-2338.
[11] 徐金济,蔡倩倩,居玲玲,等. 胸腹部肿瘤患者放射治疗依从性对摆位误差的影响分析[J].现代肿瘤医学,2023,31(21):4034-4038.
[12] 刘珠磊,步蕊蕊,周丹,等. 发泡胶热塑膜组合固定方式下头部及头颈部肿瘤质子重离子治疗中的摆位误差分析[J].医疗卫生装备,2024,45(7):56-61.
[13] 张雷,段诗苗,孙谦. 发泡胶联合热塑膜在头颈部肿瘤放疗中的应用研究[J].重庆医学,2021,50(12):2054-2056.
[14] 刘苗苗,段诗苗,陈培培,等. 发泡胶+头颈肩热塑膜在鼻咽癌螺旋断层调强放射治疗体位固定中的应用价值[J].蚌埠医学院学报,2021,46(12):1748-1750.
[15] YANG F T, LI J L, LI B,et al. Effectiveness of personalized open-face mask combined with styrofoam fixation in radiotherapy treatment of head and neck cancers:a prospective randomized controlled trial[J].Radiat Oncol,2025,20(1):34.