无痛分娩术联合缩宫素与人工破膜引产在足月妊娠孕妇中的应用效果及对hs-CRP、PCT水平的影响

doi:10.3969/j.issn.1671-7171.2025.08.009

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摘要【目的】探讨无痛分娩术联合缩宫素与人工破膜引产在足月妊娠孕妇中的应用效果及对降钙素原(PCT)、超敏C反应蛋白(hs-CRP)水平的影响。【方法】选取2024年1月至2025年1月开封市城乡一体化示范区妇幼保健院收治的116例足月妊娠孕妇,按照随机数字表法分为对照组(行无痛分娩术联合缩宫素进行引产)和观察组(行无痛分娩术联合缩宫素与人工破膜引产),每组58例。比较两组引产效果、炎症指标水平及妊娠结局。【结果】观察组第一产程、第二产程、第三产程及总产程均明显短于对照组,阴道分娩率明显高于对照组(P<0.05)。分娩后,两组hs-CRP、PCT水平高于分娩前(P<0.05),但观察组hs-CRP、PCT水平明显低于对照组(P<0.05)。两组新生儿不良结局及产妇围生期并发症总发生率比较,差异无统计学意义(P>0.05)。【结论】在足月妊娠孕妇中行无痛分娩术联合缩宫素与人工破膜进行引产,可缩短产程,提高引产效果,减轻炎症反应。

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	陈娟
	刘英杰

关键词 ：孕妇, 妊娠, 镇痛,产科, 催产素, 足月分娩, C反应蛋白质, 降钙素原

Abstract：【Objective】To explore the application effect of painless delivery combined with oxytocin and artificial rupture of membranes for induction of labor in full-term pregnant women and its impact on the levels of procalcitonin (PCT) and high-sensitivity C-reactive protein (hs-CRP). 【Methods】A total of 116 full-term pregnant women admitted to our hospital from January 2024 to January 2025 were selected and divided into a control group and an observation group according to the random number table method, with 58 cases in each group. The control group received painless delivery combined with oxytocin for labor induction, while the observation group received painless delivery combined with oxytocin and artificial rupture of membranes for labor induction. The labor induction effect, inflammatory index levels, and pregnancy outcomes were compared between the two groups. 【Results】The first stage, second stage, third stage, and total duration of labor in the observation group were significantly shorter than those in the control group, and the vaginal delivery rate was significantly higher than that in the control group (P<0.05). After delivery, the levels of hs-CRP and PCT in both groups were higher than those before delivery (P<0.05), but the levels of hs-CRP and PCT in the observation group were significantly lower than those in the control group (P<0.05). There were no statistically significant differences in the total incidence of adverse neonatal outcomes and maternal perinatal complications between the two groups (P>0.05). 【Conclusion】 For full-term pregnant women, labor induction with painless delivery combined with oxytocin and artificial rupture of membranes can shorten the labor process, improve the labor induction effect, and reduce the inflammatory response.

Key words： Pregnant Women Pregnancy Analgesia, Obstetrical Oxytocin Term Birth C-Reactive Protein Procalcitonin

收稿日期: 2025-05-07

中图分类号:

R714.3

引用本文:

陈娟, 刘英杰. 无痛分娩术联合缩宫素与人工破膜引产在足月妊娠孕妇中的应用效果及对hs-CRP、PCT水平的影响[J]. 医学临床研究, 2025, 42(8): 1324-1327.
CHEN Juan, LIU Yingjie. Application Effect of Painless Delivery Combined with Oxytocin and Artificial Rupture of Membranes for Induction of Labor in Full-Term Pregnant Women and its Impact on hs-CRP and PCT Levels. JOURNAL OF CLINICAL RESEARCH, 2025, 42(8): 1324-1327.

链接本文:

http://journal07.magtech.org.cn/yxlcyj/CN/10.3969/j.issn.1671-7171.2025.08.009 或 http://journal07.magtech.org.cn/yxlcyj/CN/Y2025/V42/I8/1324

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