Abstract：【Objective】To investigate the effects of traditional Chinese medicine (TCM) fumigation and washing therapy on the severity of pruritus and renal function in patients with uremic pruritus (UP). 【Methods】 A total of 92 patients with UP were randomly divided into the control group and the observation group, with 46 patients in each group. The control group received routine hemodialysis combined with calamine lotion, while the observation group additionally received TCM fumigation and washing for 8 consecutive weeks. Clinical efficacy, pruritus symptom scores, TCM syndrome scores, renal function [blood urea nitrogen (BUN), serum creatinine (SCr)], and calcium-phosphorus metabolism indicators [parathyroid hormone (PTH), serum phosphorus, serum calcium] were compared between the two groups before and after treatment. 【Results】 The overall effective rate in the observation group was significantly higher than that in the control group (P<0.05). After treatment, pruritus severity, pruritus area, pruritus frequency, sleep disturbance scores, TCM syndrome scores, as well as BUN, SCr, PTH, and serum phosphorus levels decreased significantly in both groups, while serum calcium levels increased (P<0.05). Moreover, improvements in all parameters were more significant in the observation group compared to the control group (P<0.05). 【Conclusion】 TCM fumigation and washing treatment can effectively alleviate pruritus symptoms in UP patients and exert a positive effect on improving renal function and regulating calcium-phosphorus metabolism.
郑华娟, 游桦, 张晴. 中药熏洗法对尿毒症皮肤瘙痒症患者皮肤瘙痒程度及肾功能的影响[J]. 医学临床研究, 2025, 42(11): 1944-1946.
ZHENG Huajuan, YOU Hua, ZHANG Qing. Effects of Traditional Chinese Herbal Fumigation and Washing Treatment on Pruritus Severity and Renal Function in Patients with Uremic Pruritus. JOURNAL OF CLINICAL RESEARCH, 2025, 42(11): 1944-1946.
2025, Vol. 42 
