Relationship of Disease Severity with the Characteristics and Morphological Changes of IVBA Plaques in Patients with Posterior Circulation Ischemia Evaluated by MRI and MSCT
FAN Xiaoling, GAO Lan
Department of Medical Imaging, Baoji People's Hospital, Baoji Shaanxi 721000
Abstract：【Objective】To explore the relationship of disease severity with the characteristics and morphological changes of intracranial vertebrobasilar artery (IVBA) plaques in patients with posterior circulation ischemia evaluated by magnetic resonance imaging (MRI) and multi-slice spiral CT (MSCT). 【Methods】A retrospective analysis was conducted on the clinical data of 90 patients with posterior circulation ischemia admitted to our hospital from February 2019 to December 2022. Based on the MRI examination results, patients with infarction lesions were included in the infarction group, while those without infarction lesions but with corresponding symptoms were included in the TIA group. MRI and MSCT examinations were performed within one week to compare the distribution, characteristics, and geometric morphology of intracranial IVBA plaques between the two groups of patients. 【Results】The MSCT examination results showed a total of 102 plaques in 90 IVBA patients, including 32 plaques (31.37%) detected in the initial segment of vertebral artery, 26 plaques (25.49%) detected in the basilar artery segment of vertebral artery, and 23 plaques (22.55%) detected in the intracranial segment of the vertebral artery. The detection rate of soft plaques in the cerebral infarction group was higher than that in the TIA group, while the detection rate of hard plaques was lower than that in the TIA group, and the differences were statistically significant (P<0.05). The true length, tortuosity rate, plaque area, and plaque burden of the basal artery in the cerebral infarction group were greater than those in the TIA group, and the differences were statistically significant (P<0.05). The lesion vascular lumen area in the cerebral infarction group was lower than that in the TIA group, and the difference was statistically significant (P<0.05). The proportion of unilateral vertebral artery dominance in the cerebral infarction group was higher than that in the TIA group, and the proportion of equally thick vertebral arteries on both sides was lower than that in the TIA group, with statistical significance (P<0.05). 【Conclusion】The characteristics and morphological abnormalities of intracranial IVBA plaques in patients with posterior circulation ischemia are closely related to the occurrence of cerebral infarction. MRI and MSCT examinations can detect and evaluate IVBA lesions in patients.
樊小玲, 高岚. MRI、MSCT评估后循环缺血患者颅内IVBA斑块特征、形态改变与病情程度的相关性[J]. 医学临床研究, 2025, 42(1): 78-81.
FAN Xiaoling, GAO Lan. Relationship of Disease Severity with the Characteristics and Morphological Changes of IVBA Plaques in Patients with Posterior Circulation Ischemia Evaluated by MRI and MSCT. JOURNAL OF CLINICAL RESEARCH, 2025, 42(1): 78-81.
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2025, Vol. 42 
