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医学临床研究  2024, Vol. 41 Issue (5): 697-699    DOI: 10.3969/j.issn.1671-7171.2024.05.015
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集成愈伤片治疗骨质疏松性胸腰椎压缩性骨折的临床疗效*
李涛, 张斌
长沙市中医医院(长沙市第八医院)脊柱外科,湖南 长沙 410002
Clinical Efficacy of Jicheng Yushang Tablets in the Treatment of Osteoporotic Thoracolumbar Compression Fractures
LI Tao, ZHANG Bin
Department of Spinal Surgery, Changsha Hospital of Traditional Chinese Medicine,Changsha Hunan 410002
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摘要 【目的】探讨集成愈伤片治疗骨质疏松性胸腰椎压缩性骨折(osteoporosis vertebra compressed fracture,OVCF)的临床疗效。【方法】选取2022年6月至2023年6月在本院行保守治疗的64 例 OVCF 患者,按随机数字表法分为观察组和对照组,每组32例。对照组在基础治疗的同时给予钙尔奇D600片联合阿法骨化醇治疗,观察组在对照组基础上加用本院院内制剂集成愈伤片治疗,均治疗3个月。比较两组治疗前、治疗1周后、治疗4周后、治疗3个月后视觉模拟评分法(VAS)评分、Oswestry 残损指数(oswestry dability index, ODI)、中医症状体征/中医证候评分,比较两组治疗前、治疗3个月后骨密度、伤椎Cobb角、伤椎高度恢复率、Cobb角改善率。【结果】治疗3个月后,观察组VAS评分、ODI、中医症状体征/中医证候评分均优于对照组(P<0.05),但在早期(治疗1周后、治疗4周后),两组上述指标比较,差异无统计学意义(P>0.05)。观察组治疗3个月后骨密度值较对照组明显改善(P<0.05);两组治疗3个月后伤椎高度恢复率、Cobb角改善率比较,差异无统计学意义(P>0.05)。【结论】集成愈伤片治疗OVCF患者,可减轻疼痛,改善患者功能障碍、症状和体征,值得临床推广应用。
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李涛
张斌
关键词 骨质疏松/并发症脊柱骨折/病因学胸椎腰椎    
Abstract:【Objective】To explore the clinical efficacy of Jicheng Yushang tablets in the treatment of osteoporotic thoracolumbar vertebral compression fractures (OVCF).【Methods】A total of 64 OVCF patients who underwent conservative treatment in our hospital from June 2022 to June 2023 were selected and randomly divided into an observation group and a control group, with 32 cases in each group, using a random number table method. The control group was treated with calcium carbonate D600 tablets combined with alpha calciferol in addition to basic treatment, while the observation group was treated with our hospital's Jicheng Yushang with callus tablets in addition to the control group, both of which were treated for 3 months.We compared the visual analogue scale (VAS) scores Oswestry Disability Index (ODI), Traditional Chinese Medicine Symptoms and Signs/TCM Syndrome Score between two groups before treatment, 1 week after treatment, 4 weeks after treatment, and 3 months after treatment. The two groups were compared in terms of bone density, Cobb angle of injured vertebrae, and recovery rate of injured vertebrae height and Cobb angle improvement rate before and after 3 months of treatment.【Results】After 3 months of treatment, the VAS score of the observation group ODI,the scores of traditional Chinese medicine symptoms and signs/syndromes were better than those of the control group (P<0.05). However, in the early stages (after 1 week and 4 weeks of treatment), there was no statistically significant difference in the above indicators between the two groups (P>0.05). After 3 months of treatment, the bone density value in the observation group was significantly improved compared to the control group (P<0.05), and the recovery rate of injured vertebral height in both groups after 3 months of treatment was not significant, there was no statistically significant difference in the improvement rate of Cobb angle (P>0.05).【Conclusion】Jicheng Yushang tablets can alleviate pain, improve functional impairments, symptoms, and signs in patients with OVCF, and are worthy of clinical promotion and application.
Key wordsOsteoporosis/CO    Spinal Fractures/ET    Thoracic Vertebrae    Lumbar Vertebrae
收稿日期: 2023-10-08     
中图分类号:  R683  
基金资助:*湖南中医药大学校级科研基金项目(编号2022XYLH101)
引用本文:   
李涛, 张斌. 集成愈伤片治疗骨质疏松性胸腰椎压缩性骨折的临床疗效*[J]. 医学临床研究, 2024, 41(5): 697-699.
LI Tao, ZHANG Bin. Clinical Efficacy of Jicheng Yushang Tablets in the Treatment of Osteoporotic Thoracolumbar Compression Fractures. JOURNAL OF CLINICAL RESEARCH, 2024, 41(5): 697-699.
链接本文:  
http://journal07.magtech.org.cn/yxlcyj/CN/10.3969/j.issn.1671-7171.2024.05.015     或     http://journal07.magtech.org.cn/yxlcyj/CN/Y2024/V41/I5/697
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