医学临床研究
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医学临床研究  2020, Vol. 37 Issue (9): 1303-1305    DOI: 10.3969/j.issn.1671-7171.2020.09.008
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下咽癌患者的临床特征与生存状况研究
胡克波1, 何恒胜2, 余婷婷1
1.四川省渠县人民医院耳鼻咽喉-头颈外科,四川 达州 635200;
2.四川省中西医结合医院耳鼻喉科,四川 成都 610000
Clinical Characteristics and Survival Status of Patients with Hypopharyngeal Carcinoma
HU Ke-bo, HE Heng-sheng, YU Ting-ting
Otolaryngology-Head and Neck Surgery,Sichuan Quxian People's Hospital,Dazhou, Sichuan,635200
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摘要 【目的】 探讨下咽癌患者的临床特征与生存状况。【方法】 回顾性分析本院收治的148例下咽癌患者的临床资料,根据患者的5年存活率将患者分为生存组55例和死亡组93例,比较两组患者的年龄,性别,是否吸烟,T分级,N分级,病灶部位,临床分级,功能状态(PS)评分和治疗方法,通过单因素分析确定下咽癌患者生存状况的相关影响因素,通过多因素分析确定下咽癌患者生存状况的独立影响因素。【结果】 通过单因素分析确定下咽癌患者生存状况的相关影响因素包括是否吸烟,T分级,N分级,临床分级,PS评分和治疗方法(P<0.05);多因素分析显示是否吸烟,T分级,N分级,PS评分和治疗方法均为下咽癌患者生存状况的独立影响因素(P<0.05)。148例患者中5年内并发症总发生率为17.6%(26/148)。【结论】 下咽癌患者生存状况的影响因素包括吸烟,病情TNM分期以及手术治疗方式,为了提升患者的生存率,应该以联合治疗为主。
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胡克波
何恒胜
余婷婷
关键词 下咽肿瘤存活率    
Abstract【Objective】 To investigate the clinical characteristics and survival status of patients with hypopharyngeal carcinoma. 【Methods】 A retrospective analysis of the clinical data of 148 patients with hypopharyngeal carcinoma admitted to our hospital was analyzed. According to the patient's 5-year survival rate, patients were divided into the survival group of 55 cases and the death group of 93 cases. The age, gender, smoking status, T grade, N grade, lesion location, clinical grade, functional status (PS) score, and treatment methods were compared between the two groups. The factors affecting the survival status of patients with hypopharyngeal carcinoma were determined by univariate analysis. Independent factors influencing the survival of patients with hypopharyngeal carcinoma were determined by multivariate analysis. 【Results】 Univariate analysis showed that the factors influencing the survival of patients with hypopharyngeal carcinoma included smoking, T grade, N grade, clinical grade, PS score, and treatment. Multivariate analysis also showed that smoking, T grade, N grade,PS score, and treatment were independent factors influencing the survival of patients with hypopharyngeal cancer. Among the 148 patients, the total number of complications in 5 years was 26, with an incidence of 17.6%.【Conclusion】 The factors influencing the survival status of patients with hypopharyngeal carcinoma include smoking, TNM staging and surgical treatment. In order to improve the survival rate of patients, the combined therapy should be the main treatment.
Key wordsHypopharyngeal Neoplasms    Survival Rate
收稿日期: 2019-04-02     
PACS:  R739.63  
基金资助:2016年四川省卫生和计划生育委员会科研课题(项目编号: 16PJ221)
引用本文:   
胡克波, 何恒胜, 余婷婷. 下咽癌患者的临床特征与生存状况研究[J]. 医学临床研究, 2020, 37(9): 1303-1305.
HU Ke-bo, HE Heng-sheng, YU Ting-ting. Clinical Characteristics and Survival Status of Patients with Hypopharyngeal Carcinoma. JOURNAL OF CLINICAL RESEARCH, 2020, 37(9): 1303-1305.
链接本文:  
http://journal07.magtech.org.cn/yxlcyj/CN/10.3969/j.issn.1671-7171.2020.09.008     或     http://journal07.magtech.org.cn/yxlcyj/CN/Y2020/V37/I9/1303
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