Abstract：【Objective】To explore the effects of different sentinel lymph node (SLN) incisions on lymph node detection and subcutaneous effusion in breast-conserving surgery for breast cancer. 【Methods】A total of 135 female breast cancer patients who underwent breast-conserving surgery from June 2017 to April 2023 were selected and divided into the observation group (n=67) and the control group (n=68) according to different SLN incision methods. The control group received axillary incisions, while the observation group received periareolar incisions. The two groups were compared in terms of SLN detection, subcutaneous effusion, quality of life, surgery-related indicators, and incidence of complications. 【Results】There was no statistically significant difference in SLN detection between the observation group and the control group (P>0.05). The operation time of the observation group was shorter than that of the control group, and the intraoperative blood loss was less than that of the control group, with statistically significant differences (P<0.05). At 3 months after surgery, the ROETC QLQ-BR45 scores and FACT-B scores of both groups were higher than those before surgery, and the observation group had higher scores than the control group, with statistically significant differences (P<0.05). There were no statistically significant differences in the incidence of complications and tumor recurrence rate between the two groups (P>0.05). 【Conclusion】Different SLN incisions have good effects in breast-conserving surgery for breast cancer, with a high number of detected SLNs, low tumor recurrence rate and subcutaneous effusion rate. However, the periareolar incision has obvious advantages in improving patients' postoperative quality of life.
刘辉. 不同前哨淋巴结切口对乳腺癌保乳手术淋巴结检出情况及并发症发生率影响[J]. 医学临床研究, 2025, 42(7): 1168-1170.
LIU Hui. Effects of Different Sentinel Lymph Node Incisions on Lymph Node Detection and Subcutaneous Effusion in Breast-Conserving Surgery for Breast Cancer. JOURNAL OF CLINICAL RESEARCH, 2025, 42(7): 1168-1170.
[1] BURSTEIN H J, CURIGLIANO G, THÜRLIMANN B, et al. Customizing local and systemic therapies for women with early breast cancer: the St. Gallen International Consensus Guidelines for treatment of early breast cancer 2021[J].Ann Oncol,2021,32(10):1216-1235.
[2] 林明,王睿琳.改良根治术与早期乳腺癌保乳手术的疗效及对患者创伤后应激障碍发生的影响[J].实用癌症杂志, 2021,36(3):475-478.
[3] 杨丽,何建信,张春霞,等.切口选择对女性浸润性乳腺癌前哨淋巴结检出及皮下积液的影响[J].安徽医药, 2022,26(8):1623-1626.
[4] 魏常胜,骆成玉,张树琦.环乳晕切口联合乳腔镜腋窝淋巴结清扫在早期乳腺癌保乳手术中的应用[J].首都医科大学学报, 2021,42(6):1014-1020.
[5] 甘文彬.盐酸肾上腺素局麻后经乳晕切口进行乳腺手术治疗对病变组织的清除情况[J].沈阳药科大学学报, 2021, 38(S01):2.
[6] 中国抗癌协会乳腺癌专业委员会. 中国抗癌协会乳腺癌诊治指南与规范(2017年版)[J].中国癌症杂志, 2017, 27(9):695-759.
[7] BJELIC-RADISIC V, CARDOSO F, CAMERON D, et al. An international update of the EORTC questionnaire for assessing quality of life in breast cancer patients: EORTC QLQ-BR45[J].Ann Oncol,2020, 31(2):283-288.
[8] 陈洁,陈秀华.乳腺癌PICC化疗应用配偶赋能认知教育的效果及对不良情绪、FACT-B评分的影响[J].河北医药, 2022,44(4):581-584.
[9] JOKAR N, VELIKYAN I, AHMADZADEHFAR H, et al. Theranostic approach in breast cancer: a treasured tailor for future oncology[J].Clin Nucl Med,2021,46(8):410-420.
[10] JAGSI R, MASON G, OVERMOYER B A, et al.Inflammatory breast cancer defined: proposed common diagnostic criteria to guide treatment and research[J].Breast Cancer Res Treat,2022,192(2):235-243.
[11] 赵永杰,吴永伟,屈翰.布托啡诺联合右美托咪定超前镇痛对乳腺癌保乳手术患者术后镇痛的效果观察[J].实用癌症杂志, 2021,36(11):1810-1817.
[12] 梁欣,刘维,荆海红.早期乳腺癌患者改良根治术与保乳手术治疗的效果及对患者术后生活质量的影响[J].实用癌症杂志, 2021,36(5):793-795.
[13] 王模日根,杨雨民.保乳手术与改良根治术治疗早期乳腺癌的疗效及并发症发生率观察[J].沈阳药科大学学报, 2021,38(2):38.
[14] 于铭,吴运舸,陈柳茵,等.腔镜下经小切口腋胸入路与乳腺入路治疗单侧甲状腺微小乳头状癌的应用比较[J].河北医药, 2023,45(15):2294-2297.
2025, Vol. 42 
