Abstract：【Objective】To explore the myocardial injury and changes in T lymphocytes in children with rotavirus enteritis and their correlation. 【Methods】 A retrospective analysis was conducted on 80 children with rotavirus enteritis admitted to our hospital from January 2019 to January 2022 (observation group). According to the severity of dehydration, the observation group was divided into non dehydration group (n=26), mild dehydration group (n=32), and moderate dehydration group (n=22). Another 80 children with enteritis who tested negative for rotavirus and were admitted to our hospital during the same period were selected as the control group. Myocardial injury biomarkers between two groups and cases with different degrees of dehydration [Creatine kinase (CK), creatine kinase isoenzyme (CK-MB), lactate dehydrogenase (LDH), α-hydroxybutyrate dehydrogenase (α-HBDH)] levels and T lymphocyte subpopulations (CD3+, CD4+, CD8+, and calculate the CD4+/CD8+ ratio) were compared.【Results】The levels of CK, CK-MB, LDH, and α-HBDH in the observation group were significantly higher than those in the control group, with statistical significance (P<0.05). The levels of CK, CK-MB, LDH, and α-HBDH in the mild and moderate groups of children were higher than those in the non dehydration group, while those in the moderate group were higher than those in the mild group, with statistical significance (P<0.05). The CD8+ in the observation group was higher than that in the control group, and the CD3+, CD4+, and CD4+/CD8+ values were lower than those in the control group, with statistical significance (P<0.05). The CD8+ levels in the mild and moderate groups were higher than those in the non dehydrated group, and the levels of CD3+, CD4+, and CD4+/CD8+ were lower than those in the non dehydrated group. Moreover, the above indicators in the mild group were significantly different from those in the moderate group (P<0.05). 【Conclusion】Myocardial injury markers and T lymphocyte subsets can accurately evaluate the dehydration status of children with early-stage viral enteritis, which is of great significance for guiding clinical treatment in the later stage.
张晓梅, 赵云爱. 轮状病毒肠炎患儿心肌损伤标志物及T淋巴细胞亚群水平观察[J]. 医学临床研究, 2023, 40(12): 1926-1928.
ZHANG Xiaomei,ZHAO Yunai. Observation of Myocardial Injury Markers and T Lymphocyte Subsets in Children with Rotavirus Enteritis. JOURNAL OF CLINICAL RESEARCH, 2023, 40(12): 1926-1928.
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2023, Vol. 40 
