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| Comparison of Multislice Spiral CT Features in Patients with Different Pathological Subtypes of Primary Lung Adenocarcinoma |
| ZHANG Wenyan, SONG Zhenyu |
| Department of Pathology, Zhengzhou People's Hospital, Zhengzhou Henan 450003 |
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Abstract 【Objective】To compare the multislice spiral computed tomography (MSCT) features of patients with different pathological subtypes of primary lung adenocarcinoma. 【Methods】The clinical data of 103 patients with primary lung adenocarcinoma who were diagnosed and treated at Zhengzhou People's Hospital from January 2021 to June 2023 were retrospectively analyzed. All patients underwent chest CT scanning and were classified, according to the classification criteria of lung adenocarcinoma, into adenocarcinoma in situ (AIS), minimally invasive adenocarcinoma (MIA), and invasive adenocarcinoma (IAC). Relevant clinical data and MSCT features were compared among the three groups. 【Results】 Among the 103 patients with primary lung adenocarcinoma, 54 (52.43%) were in the AIS group, 27 (26.21%) in the MIA group, and 22 (21.36%) in the IAC group. There were no significant differences among the three groups in aspect of age, sex, or lesion location (all P>0.05). The lymph node metastasis rates in the MIA and IAC groups were 33.33% (9/27) and 86.36% (19/22), respectively, which were both higher than that in the AIS group (all P<0.05); And the lymph node metastasis rate in the IAC group was higher than that in the MIA group (P<0.05). The postoperative recurrence rates in the MIA and IAC groups were 22.22%(6/27) and 36.36%(8/22), respectively, both higher than that in the AIS group (all P<0.05); however, there was no significant difference between the MIA and IAC groups (P>0.05). The incidences of spiculation, lobulation, and vascular convergence in the IAC group were higher than those in the AIS and MIA groups (all P<0.05). There were no significant differences among the three groups in the incidences of air bronchogram and pleural indentation (all P>0.05). The mean nodule diameter and mean CT attenuation value showed a gradual increasing trend across the AIS, MIA, and IAC groups, with significant differences between each pair of groups (all P<0.05). 【Conclusion】 Patients with different pathological subtypes of primary lung adenocarcinoma exhibit significant differences in MSCT features. Understanding these characteristic imaging findings may provide clinical value for the diagnosis and treatment of patients with primary lung adenocarcinoma.
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Received: 03 March 2026
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