肺超声分度对新生儿呼吸窘迫综合征预后不良的预测价值<sup>*</sup>

doi:10.3969/j.issn.1671-7171.2026.09.005

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Abstract 【Objective】To investigate the predictive value of lung ultrasound scoring (LUS) for poor prognosis in neonatal respiratory distress syndrome (NRDS). 【Methods】A total of 50 neonates with neonatal respiratory distress syndrome admitted to Puyang Oilfield General Hospital from January 2022 to October 2025 were enrolled. According to the prognosis after 7 days of treatment, the patients were divided into the good prognosis group (n=34) and the poor prognosis group (n=16). General data were compared between the two groups. Spearman rank correlation analysis was used to evaluate the correlations of LUS with blood routine parameters, blood gas analysis parameters, and clinical grading. Receiver operating characteristic (ROC) curve analysis was used to evaluate the predictive value of LUS for poor prognosis in NRDS after 7 days of treatment. 【Results】LUS was negatively correlated with white blood cell count (P<0.05), but showed no correlation with neutrophil percentage, lymphocyte percentage, pre-treatment pH, arterial partial pressure of oxygen (PaO₂), or clinical grading (all P>0.05). Among the 50 neonates, 34 had a good prognosis (the good prognosis group) and 16 had a poor prognosis (the poor prognosis group). There were statistically significant differences between the two groups regarding body length, body weight, whether ventilator use duration ≥7 days, LUS, and oxygenation index (all P<0.05). There were no statistically significant differences between the two groups in terms of 1-minute Apgar score, white blood cell count, neutrophil percentage, lymphocyte percentage, CRP, pre-treatment pH, or PaO₂ (all P>0.05). The area under the ROC curve of LUS for predicting poor prognosis in NRDS after 7 days of treatment was 0.692, with a sensitivity of 27.00% and a specificity of 71.00%. 【Conclusion】LUS shows no significant correlation with clinical grading in neonatal respiratory distress syndrome, but it has important clinical value in predicting poor prognosis in neonatal respiratory distress syndrome.

Key words： Neonatal Respiratory Distress Syndrome Lung Ultrasound Grading Poor Prognosis

Received: 25 December 2025

PACS:

R725.638

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	Articles by authors
	GUO Fengjuan
	LIANG Guosheng
	BIAN Fubao
	GE Jianli
	ZHANG Zhiling
	LI Kaizhen

Cite this article:

GUO Fengjuan,LIANG Guosheng,BIAN Fubao, et al. Predictive Value of Lung Ultrasound Scoring for Poor Prognosis in Neonatal Respiratory Distress Syndrome[J]. JOURNAL OF CLINICAL RESEARCH, 2026, 43(9): 1423-1426.

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http://journal07.magtech.org.cn/yxlcyj/EN/10.3969/j.issn.1671-7171.2026.09.005 OR http://journal07.magtech.org.cn/yxlcyj/EN/Y2026/V43/I9/1423

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