|
|
|
| Ultrasound Features of Juvenile Xanthogranuloma in Children |
| HUANG Ting, HU yuan, LIU Jinqiao |
| Department of Ultrasound, the Affiliated Children's Hospital of Xiangya School of Medicine, Central South University (Hunan Children's Hospital), Changsha Hunan 410007 |
|
|
|
|
Abstract 【Objective】 To explore the ultrasonic features of juvenile xanthogranuloma (JXG). 【Methods】 The ultrasonic image data of 25 children with JXG, who underwent surgical resection and were pathologically confirmed in our hospital from January 2018 to December 2025, were collected, and the ultrasonic features of JXG in children were analyzed. 【Results】 Among the 25 children with JXG, 22 cases were cutaneous juvenile xanthogranuloma (CJXG), and the main ultrasonic manifestations were single or multiple hypoechoic nodules in the subcutaneous soft tissue with clear boundaries and regular shapes. Some nodules had linear hyperechoic bands inside, and the blood flow signals inside the nodules were mainly punctate or no blood flow signals. Three cases were systemic juvenile xanthogranuloma (SJXG), involving in the liver 3 cases, in the kidney 1 case, and in the pancreas 1 case. The main manifestations were single or multiple homogeneous or heterogeneous hypoechoic nodules in different organs, with some nodules having linear hyperechoic bands inside and punctate blood flow signals inside. 【Conclusion】 The ultrasonic features of JXG have certain specificity and have clinical value for the auxiliary diagnosis of JXG.
|
|
Received: 11 August 2025
|
|
|
|
|
|
[1] 唐鹏跃, 李建红, 冯进云, 等. 幼年性黄色肉芽肿85例临床分析[J].中国麻风皮肤病杂志, 2021, 37(9): 581-584.
[2] WEE L W Y, LING H Y, HO V P Y, et al. Juvenile xanthogranulomas in Asian children[J].Dermatol Ther,2022, 35(2): e15224.
[3] 高惠, 唐婧伟, 温洁馨, 等. 皮肤型幼年性黄色肉芽肿高频超声表现[J].临床超声医学杂志, 2021, 23(11): 860-862.
[4] GINAT D T, VARGAS S O, SILVERA V M, et al. Imaging Features of Juvenile Xanthogranuloma of the Pediatric Head and Neck[J].AJNR Am J Neuroradiol,2016, 37(5): 910-916.
[5] CHALARD F, NGUYEN T, MOREL B, et al. Juvenile Xanthogranuloma of the head and neck: imaging findings in 11 cases[J].J Pediatr Hematol Oncol,2024, 46(6): e368-e380.
[6] 赵卓非, 刘军, 马嘉君, 等. 腮腺鳞状细胞癌的超声表现[J].中国超声医学杂志, 2023, 39(8): 845-848.
[7] XU J S, MA H Y, YAO X F, et al. Frequent detection of genetic aberrations reveals novel pathogenesis and treatment modalities in systemic juvenile xanthogranuloma[J].Pediatr Investig,2023, 7(3): 212-215.
[8] MCCLAIN K L. Histiocytic diseases of neonates: langerhans cell histiocytosis, rosai-dorfman disease, and juvenile xanthogranuloma[J].Clin Perinatol,2021, 48(1): 167-179.
[9] SHIBUKI S, SAIDA T, KAMIMAKI T, et al. A case of renal involvement in juvenile xanthogranulomatosis[J].Radiol Case Rep,2022, 18(2): 460-462.
[10] 马秋红, 尹一伟, 何四平, 等. 儿童幼年性黄色肉芽肿的影像学表现[J].中国医学影像学杂志, 2024, 32(12): 1222-1227.
[11] 吴南辉, 徐明圆, 吴飞, 等. 幼年性黄色肉芽肿的临床病理学特征及分子遗传学进展[J].临床与实验病理学杂志, 2024, 40(7): 748-750.
[12] 杜燕,李书兵.超声对肝包虫病的筛查及诊断价值[J].临床超声医学杂志, 2019, 21(12): 957-958.
[13] 樊亚红, 徐丽, 张晶. 胰岛细胞瘤1例超声表现分析[J].中国误诊学杂志, 2009, 9(15): 3761-3762. |
|
|
|