|
|
|
| Observation on the Therapeutic Effect of Group Painting Therapy Combined with Clozapine in the Treatment of Chronic Schizophrenia |
| ZHANG Chunliang |
| Tianjian Anding Hospital, Tianjian 300222 |
|
|
|
|
Abstract 【Objective】To explore the therapeutic effect of group painting therapy combined with clozapine in the treatment of chronic schizophrenia. 【Methods】A total of 100 patients with chronic schizophrenia who were hospitalized in our hospital from February 2019 to February 2023 were selected as the study subjects. They were randomly divided into the observation group and the control group using a random number table method, with 50 cases in each group. The control group received treatment with clozapine, while the observation group received a combination of group painting therapy on the basis of the control group. We compared the clinical efficacy of two groups and evaluated their positive and negative symptom scale (PANSS), quality of life scale for schizophrenia patients (SQLS), and social function assessment scale for hospitalized psychiatric patients (SSPI). We also compared the incidence of adverse reactions between the two groups. 【Results】The total effective rate of the observation group was higher than that of the control group, and the difference was statistically significant (P<0.05). After treatment, the positive factor score, negative factor score, general psychopathological score, and total score of the two groups were significantly lower than before treatment, and the observation group was lower than the control group, with statistical significance (P<0.05); The scores and total scores of psychosocial, energy and motivation, symptoms and side effects in the two groups of patients were lower than before treatment, and the observation group was lower than the control group, with statistical significance (P<0.05); The daily life function, motility and social interaction, social activity skill scores, and total scores of the two groups were lower than before treatment, and the observation group was lower than the control group, with statistical significance (P<0.05). There was no statistically significant difference in the incidence of adverse reactions between the two groups of patients (P>0.05).【Conclusion】The combination of group painting therapy and clozapine has significant clinical efficacy in the treatment of chronic schizophrenia, which can effectively improve the positive and negative symptoms of patients, as well as improve their quality of life and social function, with high safety.
|
|
Received: 18 May 2023
|
|
|
|
|
|
[1] 宋艳宁,陈永超,张慧英,等.豫南地区精神分裂症患者氯氮平高血药浓度的影响因素及风险预测模型的构建[J].中国医院药学杂志,2022,42(16):1668-1672.
[2] 肖剑英,蔡溢,漆靖,等.支持性-表达性团体心理治疗对首发精神分裂症患者急性期疗效的影响[J].中国医师杂志,2021,23(3):452-454.
[3] 沈渔邨.精神病学[M]. 5版.北京:人民卫生出版社,2006:503.
[4] 舒良.精神分裂症防治指南[M].北京:北京大学医学出版社,2007:1-39.
[5] 司天梅,杨建中,舒良,等.阳性和阴性症状量表(PANSS,中文版)的信、效度研究[J].中国心理卫生杂志,2004,18(1):45.
[6] 李洁,周涵辉,肖勃,等.精神分裂症病人生活质量量表信度、效度测试报告[J].中国心理卫生杂志,2003,17(11):778-780.
[7] 司天梅,舒良,田成华,等.个体和社会功能量表中文版在精神分裂症患者中的信效度[J].中国心理卫生杂志,2009,23(11):790-794.
[8] 董芳,李安宁,史犇,等.氯氮平片在中国精神分裂症患者中的生物等效性研究[J].中国临床药理学杂志,2020,36(16):2486-2489.
[9] 魏春燕,赵东荣,朱雅雯,等.团体认知行为疗法对住院精神分裂症患者自杀风险的干预效果观察[J].中国临床心理学杂志,2021,29(1):195-199.
[10] 孙福静,童艳晨.氯氮平联合利培酮治疗精神分裂症的疗效及安全性[J].重庆医学,2020,49(2):297-299.
[11] 童捷,孙喜蓉,俞玮,等.团体绘画治疗改善慢性精神分裂症患者阴性症状和服药依从性的随机对照试验[J].中国心理卫生杂志,2020,34(1):11-14.
[12] 宋慧娟,沈灏,粟幼嵩,等.布南色林联合团体心理治疗慢性精神分裂症的疗效及对认知功能、社会功能和服药依从性的影响[J].现代生物医学进展,2020,20(20):3849-3869.
|
|
|
|
2024, Vol. 41 
