脑CT灌注成像联合血清T<sub>3</sub>、FT<sub>4</sub>对早期重型颅脑损伤的诊断价值

doi:10.3969/j.issn.1671-7171.2022.08.027

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Abstract 【Objective】To explore the value of CT perfusion imaging (CTPI) combined with serum triiodothyronine (T₃) and free thyroxine (FT₄) in the diagnosis of early severe traumatic brain injury (sTBI). 【Methods】 The clinical data of 80 patients with early sTBI admitted to our hospital from January 2018 to December 2021 were retrospectively analyzed. According to the Glasgow Coma Scale (GCS) after admission, they were included in the severe group (n=43) and the mild to moderate group (n=37). Cerebral CTPI was performed in both groups to compare the regional cerebral blood flow parameters and serum T₃, FT₄ levels in the two groups, and the regional cerebral blood flow parameters and serum T₃, FT₄ levels and GCS in the severe group. The correlation between GCS and regional cerebral blood flow parameters, serum T₃ and FT₄ levels was analyzed. 【Results】 The levels of rCBV, rCBF, serum T₃ and FT₄ in the severe group were lower than those in moderate group, and MTT was higher than that in the mild and moderate group (P<0.05). On the 7th day after operation, the rCBV, rCBF, GCS scores, serum T₃ and FT₄ levels in the severe group were higher than those on the next day after admission, and the MTT was higher than that on the next day after admission. The difference was statistically significant (P<0.05). Pearson correlation analysis showed that GCS was negatively correlated with rCBV and serum T₃ and FT₄ levels (r=-0.4003,-0.6841,-0.7136,all P<0.05), but not with rCBF and MTT (P>0.05). 【Conclusion】 The combination of brain CTPI and serum T₃, FT₄ in the diagnosis of early sTBI is helpful to evaluate the degree of brain injury and to improve the diagnostic accuracy.

Key words： Craniocerebral Trauma/DI Tomography, Spiral Computed Triiodothyronine/BL Thyroxine/BL

Received: 08 March 2022

PACS:

R651.15

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	LIU Ben
	LI Yan-long
	LU Zhi-wei
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Cite this article:

LIU Ben,LI Yan-long,LU Zhi-wei, et al. Application Value of CT Perfusion Imaging Combined with Serum T₃ and FT₄ in Diagnosis of Early Severe Traumatic Brain Injury[J]. JOURNAL OF CLINICAL RESEARCH, 2022, 39(8): 1221-1223.

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http://journal07.magtech.org.cn/yxlcyj/EN/10.3969/j.issn.1671-7171.2022.08.027 OR http://journal07.magtech.org.cn/yxlcyj/EN/Y2022/V39/I8/1221

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