Abstract【Objective】To investigate the value of contrast-enhanced ultrasound (CEUS) in the diagnosis of papillary thyroid carcinoma (PTC). 【Methods】Ninety patients with PTC confirmed by pathology (the PTC group) and 90 patients with benign thyroid nodules (the control group) were enrolled in our hospital. CEUS was used to compare the peak intensity of contrast-enhanced curve-intensity curve between the two groups(PEAK), peak time (TTP), local blood volume (RBV), local blood flow (RBF), maximum perfusion intensity (SImax), mean perfusion intensity (SImean), and contrast-enhanced ultrasound mode results. 【Results】The values of PEAK, RBF, SImax and SImean in the PTC group were lower than those in the control group (P<0.05). TTP and RBV values in the PTC group were not significantly different from those in the control group (P>0.05). There was no significant difference in the uniform enhancement, enhancement intensity, and early regression between the PTC group and the control group (P>0.05). If the gold standard for diagnosis was determined by pathological results, then the sensitivity of CEUS in differential diagnosis of PTC and benign thyroid nodules was 94.44% and the specificity was 86.67%. 【Conclusion】According to the characteristics of CEUS perfusion parameters, CEUS has higher sensitivity and specificity in differential diagnosis of PTC and benign thyroid nodules.
HUANG Yue,MA De-mao,HAO Ji-ping, et al. Perfusion Parameter Characteristics and Diagnostic Value of Contrast-enhanced Ultrasound in Patients with Papillary Thyroid Carcinoma[J]. JOURNAL OF CLINICAL RESEARCH, 2020, 37(12): 1811-1813.
2020, Vol. 37 
