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| Analysis of Related Factors Affecting the Clinical Prognosis of Children with Tourette's Syndrome |
| ZHOU Zi-yun, ZHANG Li-li, WEI Yan, et al |
| Wuxi Children's Hospital of Nanjing Medical University, Wuxi 214023, Jiangsu Province |
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Abstract 【Objective】To explore the related factors affecting the clinical prognosis of children with multiple tourette syndrome. 【Methods】 From December 2017 to August 2018, 75 children diagnosed with multiple tourette syndrome in the Department of Children Health of our hospital were selected. The patients were followed up for 1 year, a unified questionnaire survey scale was adopted, and univariate and multivariate Logistic regression analysis was used to analyze the related factors affecting the prognosis of the patients. 【Results】There were statistically significant differences between the improved and uncured children in terms of family history of mental illness, number of repeated illness, severity score, and number of repeated respiratory tract infections (P<0.05). Logistic regression analysis showed that the number of recurrent cases (OR=1.072,95%CI:1.030~1.116), severity score (OR=1.100,95%CI: 1.025~1.181), recurrent respiratory tract infection (OR=1.279,95%CI:1.153~1.419), and family history of mental illness (OR=0.182,95%CI: 0.034~0.964) were independent risk factors affecting the prognosis of children with TIC (P<0.05). 【Conclusion】There are many factors restricting the prognosis of Tourette's disease in children, such as the number of relapses, the severity of the disease, recurrent respiratory tract infection, etc.; fully mastering the prognostic factors of Tourette's disease and taking relevant preventive measures can effectively control the recurrence of the disease.
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Received: 22 October 2018
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[1] 赵荣香, 罗尧竞.多发性抽动症患儿预后影响因素研究分析[J].中华急诊医学杂志, 2017, 26(9):1089-1091.
[2] Eapen V, Cavanna A E, Robertson M M. Comorbidities, social impact, and quality of life in tourette syndrome[J].Front Psychiatry,2016, 7(1):97.
[3] American Psychiatric Association. Diagnostic and statistical manual of mental disorders fifth edition[M].Arlington VA:American Psychiatric Association,2013.
[4] Greene DJ, Church JA, Dosenbach NU, et al. Multivariate pattern classification of pediatric Tourette syndrome using functional connectivity MRI:[J].Dev Sci,2016, 19(4):581-598.
[5] 马学梅, 赵亚茹.多发性抽动症药物治疗进展[J].儿科药学杂志, 2016(7):53-57.
[6] 刘晓娟, 王燕莉. 儿童多发性抽动症220例分析[J].世界临床医学, 2016, 10(12):137.
[7] Evans J, Seri S, Cavanna AE. The effects of Gilles de la Tourette syndrome and other chronic tic disorders on quality of life across the lifespan: a systematic review[J].Eur Child Adolesc Psychiatry,2016, 25(9):939-948.
[8] 王丽霞, 赵林, 曹娜,等. 多发性抽动症的免疫学研究概述[J].世界最新医学信息文摘, 2017(45):31-32.
[9] 刘惠瑾, 马辉, 贾庆红,等. 中医药治疗儿童多发性抽动症的研究进展[J].临床合理用药杂志, 2016, 9(29):176-178. |
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2020, Vol. 37 
