Abstract 【Objective】 To explore the relationship between serum alkaline phosphatase and coronary artery calcification. 【Methods】 A total of 154 hospitalized patients underwent 128-layer coronary artery CT scan in Suzhou traditional Chinese Medicine Hospital. According to the coronary artery CT calcification score, the severity of coronary artery calcification was evaluated, and the serum alkaline phosphatase level was measured. The patients were divided into calcified group and non-calcified group according to the calcification score. The clinical data and ALP level of the patients in the two groups were compared, and the correlation between coronary artery calcification score and serum ALP level, age and blood lipid index in the calcified group was further analyzed.【Results】 There were significant differences in age, smoking history, diabetes mellitus history, hypertension history and serum high density lipoprotein cholesterol (HDL-C) and ALP levels between calcification group and non calcification group (P<0.05); there were no significant differences in gender, drinking history, serum total cholesterol (TC), low density lipoprotein cholesterol (LDL-C), triglyceride (TG) (P>0.05).In calcification group, calcification score was significantly positively correlated with age and ALP (P<0.01), and negatively correlated with HDL-C(P=0.016<0.05), but there was no correlation between calcification score and TC, TG, LDL-C (P>0.01).【Conclusion】 Serum alkaline phosphatase level is closely related to coronary artery calcification, which can be used as a biological index for the diagnosis of coronary artery calcification.
2020, Vol. 37 
