Abstract【Objective】To investigate the characteristics of cerebral hemodynamic changes in the early neonatal period. 【Methods】A total of 142 neonates were detected by color Doppler ultrasound in our hospital. Systolic blood flow velocity (Vs), peak diastolic blood flow velocity (Vd) and resistance index (RI) of the middle cerebral artery were measured within 24 hours, 24-48 hours and 48-72 hours after birth. Statistical methods SPSS17.0 was used for statistical analysis. 【Results】Among the 142 newborns, there were 87 males and 55 females with gestational age of 28+4-44 weeks and birth weight of 950-4650 g. The comparison of Vs(cm/s), Vd (cm/s) and RI of the middle cerebral artery within 24 hours, 24-48 hours and 48-72 hours after birth were statistically significant (P<0.01). According to the birth weight, newborn babies were divided into three groups: <1500g,1500g-2500g and >2500g. The values of Vs, Vd and RI in the three groups were compared and the differences were statistically significant (P<0.01). Meanwhile the differences of Vs, Vd and RI in three gestational age groups (<37 weeks, 37+1-42 weeks and > 42 weeks) The Vs, Vd, and RI were statistically significant (P<0.01). Also, the differences in Vs, Vd and RI among no asphyxia, mild asphyxia, moderate asphyxia and severe asphyxia groups at birth were statistically significant (P<0.01). Lastly, hemodynamic characteristics of the intrauterine distress group and the non-intrauterine distress group were compared. The result showed that the differences were statistically significant (P<0.01). 【Conclusion】The hemodynamic changes of the middle cerebral artery in early neonatal period are different. The influencing factors include birth asphyxia, intrauterine distress, gestational age and birth weight.
2019, Vol. 36 
