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| Clinical Efficacy of Traditional Chinese Medicine Retention Enema in Patients with Recurrence after Colon Polyp Resection |
| SONG Pengju, WANG Shangyuan |
| Department of Surgery, Suzhou Jinchang Hospital, Suzhou Jiangsu 215000 |
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Abstract 【Objective】 To investigate the curative effect of traditional Chinese medicine retention enema in the treatment of patients with recurrence of polyps after colon polypectomy. 【Methods】 A total of 86 patients with colonic polyp recurrence who were admitted to our hospital from April 2020 to April 2025 were selected as the research objects. According to the random number table method, they were divided into the control group of 43 cases with 5-fluorouracil enema and the observation group of 43 cases with traditional Chinese medicine enema. The clinical efficacy, polyp mucosal damage score, polyp number, polyp diameter and adverse reactions were compared between the two groups. 【Results】 The total effective rate of the traditional Chinese medicine prescription group was 90.70%(39/43), which was higher than that of the control group (67.44%, 29/43). The difference was statistically significant (P<0.05). Before treatment, there were no significant differences in the score of polyp mucosal damage, the number of polyps, and the diameter of polyps between the two groups (P>0.05). After treatment, the scores for the degree of mucosal injury, the number of polyps, and the polyp diameter in both groups were lower than their respective pre-treatment levels; furthermore, the values in the observation group were lower than those in the control group, and the difference was statistically significant (P<0.05).During the treatment period, no adverse reactions such as rashes, vomiting, nausea, or impairment of liver and kidney function were observed in either group; the difference was not statistically significant (P>0.05). 【Conclusion】 Traditional Chinese medicine retention enema demonstrates favorable clinical efficacy in the treatment of patients with recurrent colon polyps after colon polypectomy. It can significantly reduce the diameter of polyps, improve mucosal damage, and reduce the recurrence rate, which is worthy of clinical promotion.
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Received: 30 October 2025
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[1] 方宜正, 刘琦. 结直肠息肉内科诊治进展[J].贵州医药, 2016, 40(3):322-324.
[2] 李建国, 徐杨, 姜明明. 结直肠腺瘤性息肉电切术后复发危险因素及随访间期探讨[J].医学临床研究, 2013, 30(1):66-68.
[3] 王向军, 陈一秀. 结肠息肉患者中药保留灌肠液温度的选择研究[J].中医药导报, 2015,21(13):62-64.
[4] 赵旭,崔应麟,赵君颖,等. 中医灌肠疗法研究进展[J].中国中医基础医学杂志,2015,21(8):1052-1054.
[5] 王春赛尔, 李景南. 结直肠息肉发病危险因素的研究进展[J].临床内科杂志, 2016, 33(11):788-790.
[6] 崔荣,石兴耀,周勇. 内镜治疗结肠直肠息肉的临床分析(附828例报告)[J].外科理论与实践,2016,21(1):73-75.
[7] 陈建科. 中药保留灌肠治疗溃疡性结肠炎临床研究[J].中医学报,2015,30(5):731-733.
[8] 孙维彤, 陈倩倩, 张娜,等. 5-氟尿嘧啶前体药物研究进展[J].生命的化学, 2014, 34(2):269-274.
[9] 袁广众, 韩树堂, 肖君. 中西医防治结肠息肉术后复发的研究进展[J].中国临床研究, 2017, 30(5):695-697.
[10] 任常谕, 李晋奇, 童荣生. 配伍在含莪术复方临床功效发挥中的作用[J].中国药房, 2016, 27(17):2428-2430.
[11] 徐男, 黄欣, 孙蓉,等. 与三棱“功效-毒性-物质基础”相关的化学成分、制备工艺和质量控制研究进展[J].中国药房, 2016, 27(33):4749-4752.
[12] 赵志梅, 张立杰, 夏天,等. 莪术主要单体成分抗炎、抗肿瘤作用研究进展[J].药物评价研究, 2017, 40(1):119-124.
[13] 陈阳峰,钟晓红. 黄柏的药理作用及其活性成分提取[J].作物研究,2015,29(5):564-568.
[14] 安敏,邱颐. 利多卡因非麻醉作用研究进展[J].临床麻醉学杂志, 2015, 31(9):928-930. |
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