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| Clinical Effect of Bawei Tongda Decoction in Adjuvant Treatment of Patients with Variant Angina Pectoris |
| WANG Bin1, WANG Chen2, ZHANG Kangkang2 |
1. Wuxi Huishan People's Hospital, Wuxi Jiangsu 214000;
2. Wuxi Mingci Cardiovascular Hospital, Wuxi Jiangsu 214000 |
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Abstract 【Objective】 To explore the clinical effect of Bawei Tongda Decoction in adjuvant treatment of patients with variant angina pectoris. 【Methods】 A total of 80 patients with variant angina pectoris admitted to the Wuxi Mingci Cardiovascular Hospital from December 2023 to October 2024 were selected and divided into an observation group and a control group according to different treatment methods, with 40 cases in each group. The control group was given conventional western medicine treatment, and the observation group was additionally treated with Bawei Tongda Decoction on the basis of the control group. Both groups were treated continuously for 4 weeks. The clinical efficacy, TCM syndrome scores, Seattle Angina Questionnaire scores, frequency and duration of angina pectoris attacks, as well as serum levels of malondialdehyde (MDA), nitric oxide (NO) and superoxide dismutase (SOD) were compared between the two groups. 【Results】 After treatment, the frequency and duration of angina pectoris attacks in both groups were lower than those before treatment, and the observation group was lower than the control group, with statistically significant differences (P<0.05); the scores of chest pain, chest tightness, fatigue, palpitations and shortness of breath, and dark complexion in both groups were lower than those before treatment, and the observation group was lower than the control group, with statistically significant differences (P<0.05); the serum MDA level in both groups was lower than that before treatment, and the levels of NO and SOD were higher than those before treatment; in addition, the serum MDA level in the observation group was lower than that in the control group, and the levels of NO and SOD were higher than those in the control group (P<0.05); the scores of physical activity limitation, angina stability, angina attack, treatment satisfaction and disease cognition in both groups were higher than those before treatment, and the observation group was higher than the control group (P<0.05). The total effective rate of the observation group was higher than that of the control group, with a statistically significant difference (P<0.05). 【Conclusion】 Bawei Tongda Decoction has a good clinical effect in adjuvant treatment of patients with variant angina pectoris, which can effectively relieve angina pectoris symptoms, improve vascular function and enhance the quality of life of patients.
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Received: 18 April 2025
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