|
|
Efficacy of Auricular Acupoint Pressing Combined with Modified Huanglian Wendan Decoction in Treating Female Climacteric Syndrome with Sleep Disorders |
ZHANG Limin, LIU Min, ZHU Peiyu |
Zhengzhou Maternal and Child Health Hospital, Traditional Chinese Medicine Clinic, Zhengzhou Henan 450000 |
|
|
Abstract 【Objective】 To explore the efficacy of auricular acupoint pressing(press-needle implantation) combined with a modified Huanglian Wendan Decoction in treating female patients with climacteric syndrome (CMS) accompanied by sleep disorders.【Methods】Ninety-six female patients with CMS and sleep disorders were randomly divided into a control group and an observation group, with 48 patients in each group. The control group was treated with oral estazolam, while the observation group received auricular acupoint pressing(press-needle implantation) combined with a modified Huanglian Wendan Decoction. Clinical efficacy, serum hormone levels [estradiol (E2), follicle-stimulating hormone (FSH), luteinizing hormone (LH)], Traditional Chinese Medicine (TCM) syndrome scores, and sleep quality [Pittsburgh Sleep Quality Index (PSQI)] were compared between the two groups before and after treatment.【Results】 After treatment, the TCM syndrome scores, FSH levels, and PSQI scores of both groups were lower than before treatment (P<0.05), and E2 levels were higher than before treatment (P<0.05). The total effective rate and E2 levels in the observation group were higher than those in the control group, while TCM syndrome scores, FSH levels, and PSQI scores were lower than those in the control group (P<0.05).【Conclusion】 Auricular acupoint pressing combined with a modified Huanglian Wendan Decoction can significantly improve the efficacy and E2 levels in female patients with CMS and sleep disorders, while reducing TCM syndrome scores, serum FSH levels, and PSQI scores. Its clinical efficacy is superior to that of estazolam.
|
Received: 18 April 2024
|
|
|
|
|
[1] 张淼苗,张引,胡敏,等. 自助式正念减压疗法改善女性更年期综合征负性情绪的随机对照研究[J].同济大学学报(医学版),2022,43(2):254-261. [2] 李强,王强,朱晓红,等. 激素替代治疗中国围绝经期女性疗效及安全性Meta分析[J].临床军医杂志,2020,48(11):1290-1294. [3] 陈莉,马晓娟,史大卓. 激素替代疗法:获益还是风险[J].中西医结合心脑血管病杂志,2022,20(11):2012-2016. [4] 吴晓兰,尹小花,王小凤,等. 基于中医体质辨识理论探讨火龙罐疗法在更年期综合征合并睡眠障碍病人中的应用[J].护理研究,2023,37(22):4129-4135. [5] 苏亮,陆峥.2017年中国失眠症诊断和治疗指南解读[J].世界临床药物,2018,39(4):217-222. [6] 乐杰.妇产科学[M].北京:人民卫生出版社,2004:350-351. [7] 中华人民共和国卫生部.中药新药临床研究指导原则[M].北京:中国医药科技出版社,2002:243-247. [8] 沈丽,王蓓蓓,叶雯君. 5E护理模式联合正念训练对更年期女性睡眠障碍的影响[J].齐鲁护理杂志,2022,28(22):145-148. [9] 杨涛,王芳,代伟,等. 褪黑素对女性更年期综合征的临床研究进展[J].中国计划生育和妇产科,2023,15(7):63-67. [10] 张娜,王书华,王凯红. 激素替代疗法改善宫颈鳞癌术后患者更年期综合征的有效性和安全性及对其血清SCC-Ag、MMP-9的影响[J].临床和实验医学杂志,2023,22(12):1309. [11] 郑志博,刘雁峰,郭霖霖,等. 基于中医传承辅助平台分析刘雁峰治疗更年期综合征的用药规律[J].辽宁中医杂志,2022,49(9):1-4. [12] 布立影,周婷婷,耿志月,等. 内养功联合滋阴清热安神汤对女性更年期失眠患者性激素及睡眠质量影响[J].辽宁中医药大学学报,2022,24(10):169-173. [13] 吴洁,高艳,秦铎,等. 揿针埋植联合黄连温胆汤加减治疗女性更年期不寐临床疗效观察[J].湖北中医药大学学报,2023,25(6):95-97. [14] 单韵,杜少辉. 阳和汤加减方联合艾司唑仑治疗更年期睡眠障碍临床疗效观察[J].广州中医药大学学报,2020,37(9):1658-1662. |
[1] |
. [J]. JOURNAL OF CLINICAL RESEARCH, 2024, 41(8): 1261-1263. |
|
|
|
|