Abstract 【Objective】To investigate whether unmarried adolescent pregnant women have higher rates of pregnancy complications and comorbidities, and explore the impact on maternal and infant outcomes. 【Methods】A retrospective cohort study was conducted on the general characteristics and pregnancy outcomes of adolescent pregnant women aged 11-19 years and adult pregnant women over 20 years old who were hospitalized in our hospital from January 2013 to December 2020. A comparison of pregnancy complications, adverse pregnancy outcomes, and delivery methods was made, and relative risks were calculated. 【Results】There were 743 pregnant women in the adolescent group, and the number and proportion showed a downward trend year by year.The proportion of pregnant women in the adolescent group was lower in the local population (64.1% vs 90.9%), lower proportion of multiparas (7.1% vs 34.3%), higher proportion of vaginal delivery (68.1% vs 46.6%). The average delivery gestational age was [(39.6±1.7) weeks vs (39.1±1.4) weeks], the birth weight of new-borns was [(3304.9±465.4) g vs ( 3356.3±443.1) g], and hospitalization expenses was [(6594.2±3012.7) yuan vs (8547.8±3694.0) yuan] as the adolescent pregnant group vs the adult pregnant group; And the differences were statistically significant (P<0.05).The adolescent group had higher rates of anemia and preeclampsia, while gestational diabetes and hypothyroidism were less common. When compared to adults aged 20-34 years, the incidence of hypertensive disorders during pregnancy was also higher in the adolescent group. The incidence of neonatal asphyxia in the adolescent group was higher than that in the adult group. There was no significant difference in other maternal and infant outcomes between the two groups. 【Conclusion】The incidence of anemia and gestational hypertension in adolescents is higher than that in adults, and the incidence of neonatal asphyxia is higher than that in adults. Despite the declining rate of hospital deliveries of adolescent pregnancy, it is vital to pay attention to adolescent sex education in order to prevent unintended pregnancy, and it is necessary to care for adolescent pregnant women in order to reduce adverse outcomes for the mother and infant.
[1] ZHANG T, WANG H E, WANG X L, et al. The adverse maternal and perinatal outcomes of adolescent pregnancy:a cross sectional study in Hebei, China[J].BMC Pregnancy Childbirth,2020, 20(1):339. [2] MACEDO T C C, MONTAGNA E, TREVISAN C M, et al.Prevalence of preeclampsia and eclampsia in adolescent pregnancy:A systematic review and meta-analysis of 291 247 adolescents worldwide since 1969 [J].Eur J Obstet Gynecol Reprod Biol,2020, 248:177-186. [3] STANICZENKO A P, WEN T, CEPIN A G, et al. Deliveries among patients aged 11-19 years and risk for adverse pregnancy outcomes [J].Obstet Gynecol,2022, 139(6):989-1001. [4] KARATAŞLI V, KANMAZ A G, ĪNAN A H, et al. Maternal and neonatal outcomes of adolescent pregnancy [J].J Gynecol Obstet Hum Reprod,2019, 48(5):347-350. [5] KASSA G M, AROWOJOLU A O, ODUKOGBE A A, et al.Adverse neonatal outcomes of adolescent pregnancy in Northwest Ethiopia [J].PLoS One,2019, 14(6):e0218259. [6] KASSA G M, AROWOJOLU A O, ODUKOGBE A T A, et al. Adverse maternal outcomes of adolescent pregnancy in Northwest Ethiopia:A prospective cohort study [J].PLoS One,2021, 16(9):e0257485. [7] 中华医学会计划生育学分会,国家卫生健康委科学技术研究所. 青少年避孕服务指南[J].中华妇产科杂志, 2020, 55(2):83-90. [8] YAKUBU I,SALISU W J. Determinants of adolescent pregnancy in sub-Saharan Africa:a systematic review [J].Reproductive Health,2018, 15(1):15. [9] KASSA G M, AROWOJOLU A O, ODUKOGBE A A, et al.Prevalence and determinants of adolescent pregnancy in Africa:a systematic review and Meta-analysis [J].Reprod Health,2018, 15(1):195. [10] 庄文明, 张丽, 张婧, 等. 青少年初产妇妊娠结局及影响因素研究[J].中国全科医学, 2022, 25(20):2474-2481. [11] 韦雪萍, 周莉, 李恒霄, 等. 少数民族地区低龄孕产妇的妊娠结局 [J].中华围产医学杂志, 2021, 24(8):622-626. [12] KAWAKITA T, WILSON K, GRANTZ K L, et al. Adverse maternal and neonatal outcomes in adolescent pregnancy [J].J Pediatr Adolesc Gynecol,2016, 29(2):130-136. [13] AGRAWAL A,WENGER N K. Hypertension during pregnancy [J].Curr Hypertens Rep,2020, 22(9):64. [14] LA-ORPIPAT T,SUWANRATH C. Pregnancy outcomes of adolescent primigravida and risk of pregnancy-induced hypertension:a hospital-based study in Southern Thailand [J].J Obstet Gynaecol,2019, 39(7):934-940. [15] ZILE I, EBELA I,RUMBA-ROZENFELDE I. Maternal risk factors for stillbirth:a registry-based study [J].Medicina,2019, 55(7):326.
2023, Vol. 40 
