Abstract 【Objective】 To investigate the independent risk factors affecting the surgical prognosis of patients with intrahepatic cholangiocarcinoma (ICC). 【Methods】 The clinicopathological data and prognostic information of 64 ICC patients were collected. Univariate and multivariate COX proportional hazards regression models were used to analyze the independent risk factors affecting the prognosis,and Kaplan-Meier survival curves were drawn to compare the effects of different factors on the prognosis of patients. 【Results】 Elevated carbohydrate antigen 19-9(CA19-9),extrahepatic metastasis and large duct type of ICC were independent risk factors for the prognosis of patients with ICC. The prognosis of patients with elevated CA19-9,extrahepatic metastasis and large duct ICC was poor,and the differences were statistically significant (all P<0.05). 【Conclusion】 Elevated CA19-9,extrahepatic metastasis and ICC with large duct type are independent risk factors for the prognosis of patients with ICC.
HUANG Li-yun,CHEN Yi,LYU Xu-jiang, et al. Analysis of the Influencing Factors of Surgical Prognosis in Patients with Intrahepatic Cholangiocarcinoma[J]. JOURNAL OF CLINICAL RESEARCH, 2023, 40(3): 328-331.