急性缺血性脑梗死机械取栓术后24 h内DRAGON评分联合TIBI分级对预后的预测价值

doi:10.3969/j.issn.1671-7171.2022.10.019

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Abstract 【Objective】To explore the predictive value of DRAGON score combined with TIBI within 24 hours after mechanical thrombectomy for acute ischemic cerebral infarction. 【Methods】A total of 98 patients with acute ischemic cerebral infarction who underwent mechanical thrombectomy in our hospital were selected for the study. Both 24 hour DRAGON score and TIBI grading at 24 hours after operation were evaluated. Patients were further divided into the poor prognosis group and good prognosis group according to their prognosis within 1 week after operation. Logistic multivariate regression analysis was used to explore the related factors affecting the prognosis of 1 week after mechanical thrombectomy. The receiver operating characteristic curve (ROC) was used to analyze the predictive value of DRAGON score and TIBI grading alone and in combination on recurrence of cerebral infarction within 1 week after operation.【Results】Among the ninety-eight patients, fifty-eight patients had a poor prognosis within 1 week after surgery (the poor prognosis group), accounting for 59.18%. The forty patients had a good prognosis (the good prognosis group), accounting for 40.82%. The poor prognosis group had a poor baseline CTA collateral compensation score, the proportion of TIBI grades 0 to 3, and the DRAGON score level were higher than those in the good prognosis group (P<0.05). The results of Logistic multivariate regression analysis showed that the poor baseline CTA collateral compensation score, the proportion of TIBI grades 0 to 3, and the high DRAGON score were all risk factors for poor prognosis within 1 week after surgery(P<0.05). ROC analysis showed that the area under the curve (AUC) of TIBI classification, DRAGON score and the combination of the two for acute ischemic cerebral infarction undergoing mechanical thrombectomy were 0.769, 0.785, and 0.839, respectively. The TIBI grades or DRAGON score alone had lower predictive value for poor prognosis within 1 week after operation than the combination of the two (P<0.05). 【Conclusion】TIBI grades 0 to 3 and high DRAGON scores are risk factors for poor prognosis in patients with acute ischemic cerebral infarction who underwent mechanical thrombectomy within 1 week after surgery. TIBI grading and DRAGON score alone and in combination have certain clinical predictive value in predicting the prognosis of patients with cerebral infarction undergoing mechanical thrombectomy within 1 week after surgery.

Key words： Brain Infarction/SU Acute Disease Thrombolytic Therapy Prognosis

Received: 13 April 2022

PACS:

R743.33

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	LIU Fei
	GAO Bei
	XUE Jin-e
	et al

Cite this article:

LIU Fei,GAO Bei,XUE Jin-e, et al. Predictive Value of DRAGON Score Combined with TIBI Grading within 24 hours after Mechanical Thrombectomy for Prognosis of Acute Ischemic Cerebral Infarction[J]. JOURNAL OF CLINICAL RESEARCH, 2022, 39(10): 1509-1512.

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http://journal07.magtech.org.cn/yxlcyj/EN/10.3969/j.issn.1671-7171.2022.10.019 OR http://journal07.magtech.org.cn/yxlcyj/EN/Y2022/V39/I10/1509

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